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. 2024 Feb;105(2):001963.
doi: 10.1099/jgv.0.001963.

ICTV Virus Taxonomy Profile: Kolmioviridae 2024

Jens H Kuhn  1 , Artem Babaian  2 , Laura M Bergner  3 , Paul Dény  4 , Dieter Glebe  5 , Masayuki Horie  6 , Eugene V Koonin  7 , Mart Krupovic  8 , Sofia Paraskevopoulou  9 , Marcos de la Peña  10 , Teemu Smura  11 , Jussi Hepojoki  11
Affiliations

ICTV Virus Taxonomy Profile: Kolmioviridae 2024

Jens H Kuhn et al. J Gen Virol. 2024 Feb.

Abstract

Kolmioviridae is a family for negative-sense RNA viruses with circular, viroid-like genomes of about 1.5-1.7 kb that are maintained in mammals, amphibians, birds, fish, insects and reptiles. Deltaviruses, for instance, can cause severe hepatitis in humans. Kolmiovirids encode delta antigen (DAg) and replicate using host-cell DNA-directed RNA polymerase II and ribozymes encoded in their genome and antigenome. They require evolutionary unrelated helper viruses to provide envelopes and incorporate helper virus proteins for infectious particle formation. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Kolmioviridae, which is available at ictv.global/report/kolmioviridae.

Keywords: ICTV Report; Kolmioviridae; deltavirus; hepatitis D virus; taxonomy.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Fig. 1.
Fig. 1.. Schematic of hepatitis D virus 1 particles. L-DAg, S-DAg: large and small delta antigen; L-HBsAg, M-HBsAg, S-HBsAg: large, middle and small HBV surface antigen; HBV: hepatitis B virus.
Fig. 2.
Fig. 2.. Antigenome organization of hepatitis D virus 1. Nucleotide numbering according to that for the (complementary) genome.
See this image and copyright information in PMC

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