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Review
. 2024 Apr;51(2):221-232.
doi: 10.1016/j.cps.2023.11.001. Epub 2023 Nov 23.

Inhalation Injury, Respiratory Failure, and Ventilator Support in Acute Burn Care

Sai R Velamuri  1 , Yasmin Ali  2 , Julio Lanfranco  3 , Pooja Gupta  4 , David M Hill  5
Affiliations
Review

Inhalation Injury, Respiratory Failure, and Ventilator Support in Acute Burn Care

Sai R Velamuri et al. Clin Plast Surg. 2024 Apr.

Abstract

Sustaining an inhalation injury increases the risk of severe complications and mortality. Current evidential support to guide treatment of the injury or subsequent complications is lacking, as studies either exclude inhalation injury or design limit inferences that can be made. Conventional ventilator modes are most commonly used, but there is no consensus on optimal strategies. Settings should be customized to patient tolerance and response. Data for pharmacotherapy adjunctive treatments are limited.

Keywords: Acute lung injury; Burns; Extracorporeal circulation; Inhalation injury; Mechanical; Therapeutics; Ventilators.

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Conflict of interest statement

Disclosures S.R. Velamuri is a consultant for Kerecis. Y. Ali, J. Lanfranco, P. Gupta, and D.M. Hill have received research funding and are a consultant for Medline Industries, LP and Trevena, Inc and a consultant for Access Pro Medical.