Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Feb 27:15:39-55.
doi: 10.2147/VMRR.S415339. eCollection 2024.

Rate of Beta-Lactam Resistance and Epidemiological Features of S. Aureus-Associated Bovine Mastitis in Cross-Bred Ethiopian Cows: Systematic Review

Melkie Dagnaw  1 , Marshet Bazezew  2 , Bemrew Mengistu  3 , Birhan Anagaw  4 , Atsede Solomon Mebratu  5
Affiliations
Review

Rate of Beta-Lactam Resistance and Epidemiological Features of S. Aureus-Associated Bovine Mastitis in Cross-Bred Ethiopian Cows: Systematic Review

Melkie Dagnaw et al. Vet Med (Auckl). .

Abstract

Background: Dairy cows get mastitis from a common infection called Staphylococcus aureus. Because of its broad distribution across diverse populations and capacity to acquire antibiotic resistance, this particular bacterial strain presents a serious threat to public health. The main goals of this study were to determine the beta-lactam resistance profile of S. aureus in Ethiopian dairy cows and to offer thorough epidemiological data.

Methods: We employed manual searches, Web of Science, PubMed Central, and Google Scholar HINARI for electronic bibliographic data.

Results: Twenty-six epidemiological studies were included in this systematic review. Of these studies, 12 articles in Oromia, 4 articles in Addis Ababa, 4 articles in Southern Nations, Nationalities, and People's (SNNPRS), 3 articles in Tigray, and 3 articles in Amhara region. The average prevalence S. aureus were 34.3% in Oromia, 40.2% in Amhara, 39.5 in AA, 40% in Tigray and 21% in SNNPRS. The antimicrobial resistance rate of S. aureus, specifically in relation to beta-lactam drugs, exhibited an average estimation. Notably, penicillin resistance reached a rate of 75%, while amoxicillin resistance stood at 67%. Furthermore, it was determined that, when treating S. aureus, the resistance rates to ampicillin and cephalosporin were 50% and 57%, respectively.

Conclusion: The results of this analysis have demonstrated a considerable rise in S. aureus prevalence and beta-lactam resistance within the Ethiopian geographic environment. This emphasizes the critical need for alternate therapeutic approaches and preventative measures in order to successfully lessen the disease's extensive spread and detrimental effects across the nation.

Keywords: antimicrobial resistance; beta-lactam; bovine mastitis, S. aureus; systematic review; veterinary epidemiology.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
PRISMA flow chart for selection of included and excluded of studies.
Figure 2
Figure 2
Prevalence of S. aureus in the respect of the study year.
Figure 3
Figure 3
Geographical distribution of S. aureus in Ethiopia.
Figure 4
Figure 4
Prevalence of S. aureus in different study year categories in Ethiopia.
Figure 5
Figure 5
Average prevalence of S. aureus in clinical and subclinical mastitis in Ethiopia.
Figure 6
Figure 6
Beta lactam antimicrobial resistance rate of S. aureus in the treatment of bovine mastitis.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Abebe R, Hatiya H, Abera M, Megersa B, Asmare K. Bovine mastitis: prevalence, risk factors and isolation of Staphylococcus aureus in dairy herds at Hawassa milk shed, South Ethiopia. BMC Vet Res. 2016;12:1–11. doi:10.1186/s12917-016-0905-3 - DOI - PMC - PubMed
    1. Bardhan I, Lin S. Research note—business value of information technology: testing the interaction effect of IT and R&D on Tobin’s Q. Inform Syst Res. 2013;24(4):1147–1161.
    1. Seegers H, Fourichon C, Beaudeau F. Production effects related to mastitis and mastitis economics in dairy cattle herds. Vet Res. 2003;34(5):475–491. doi:10.1051/vetres:2003027 - DOI - PubMed
    1. Mungube EO, Tenhagen B, Regassa F, Kyule MN, Shiferaw Y. Reduced milk production in udder quarters with subclinical mastitis and associated economic losses in crossbred dairy cows in Ethiopia. Trop Ani Health Produ. 2005;37(6):503–512. doi:10.1007/s11250-005-7049-y - DOI - PubMed
    1. Birhanu M, Leta S, Mamo G, Tesfaye S. Prevalence of bovine subclinical mastitis and isolation of its major causes in Bishoftu. BMC Res Notes. 2017;10(1):1–6. doi:10.1186/s13104-016-2345-3 - DOI - PMC - PubMed

LinkOut - more resources