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Case Reports
. 2024 Feb 1;16(2):e53368.
doi: 10.7759/cureus.53368. eCollection 2024 Feb.

The Use of Intralipid Infusions in the Prevention of Embryo Implantation Failure

Okorie C Anya  1 , Eniola R Ajayi  2 , Henry R Solanke  3 , Adaeze I Ohanaka  4 , Kokei D Ubana  5
Affiliations
Case Reports

The Use of Intralipid Infusions in the Prevention of Embryo Implantation Failure

Okorie C Anya et al. Cureus. .

Abstract

Intralipids have been suggested to suppress uterine natural killer cell activity, which could potentially improve implantation rates in women with recurrent loss. We report a case of a 41-year-old African woman with recurrent pregnancy loss who had elevated uterine killer cell activity and for whom intralipid infusion was used to achieve pregnancy. We recommend routine uterine natural killer cell testing for women with recurrent pregnancy loss and further research on newer intravenous lipid emulsions in fertility medicine.

Keywords: immunomodulation; in vitro fertilization; intralipid; intravenous lipid emulsion; recurrent pregnancy loss; uterine natural killer cells.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. In memory of Arvid Wretlind 1919 - 2002. Isaksson B, Hambraeus L, Vinnars E, Samuelson G, Larsson J, Asp NG. Food Nutr Res. 191920022002;46:117.
    1. When is parenteral nutrition indicated? Berger MM, Pichard C. J Intensive Med. 2022;2:22–28. - PMC - PubMed
    1. Computerized energy balance and complications in critically ill patients: an observational study. Dvir D, Cohen J, Singer P. Clin Nutr. 2006;25:37–44. - PubMed
    1. Lipid emulsions in parenteral nutrition of intensive care patients: current thinking and future directions. Calder PC, Jensen GL, Koletzko BV, Singer P, Wanten GJ. Intensive Care Med. 2010;36:735–749. - PMC - PubMed
    1. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Weinberg GL, VadeBoncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. Anesthesiology. 1998;88:1071–1075. - PubMed

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