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. 2024 Feb 28:17:489-491.
doi: 10.2147/CCID.S443182. eCollection 2024.

Anti-Spot, Lightening Effect and Cutaneous Acceptability of a Stable Anhydrous Ecobiological Formulation of 10% L-Ascorbic Acid

Elise Abric  1 , Jessica Mathias  1 , Anne-Sophie Tardieu  1 , Léa Mateos  1 , Chantal Eeckhout  1 , Fanny Drulhon  1 , Nathalie Ardiet  1
Affiliations

Anti-Spot, Lightening Effect and Cutaneous Acceptability of a Stable Anhydrous Ecobiological Formulation of 10% L-Ascorbic Acid

Elise Abric et al. Clin Cosmet Investig Dermatol. .
No abstract available

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Conflict of interest statement

All authors are employees of NAOS Ecobiology Company. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Evolution of the L* (skin lightness) (A) and ITA° (skin pigmentation degree) (B) parameters. Mean values ± SEM of the L* (A) and ITA° (B) parameters on the pigmented and normal skin zones were recorded after twice daily application of the product for 28 (D28) and 56 days (D56). Three measurements were made using a spectrophotometer per zone and time-point. ITA°= [Arc tan ((L*-50)/b*)] x 180/π. For the L* and ITA° parameters, the following changes (Δ) from baseline (T0) were calculated at each time-point (Ti) for the pigmented zone (PZ) and normal skin zone (NZ): ΔPZ= (PZ Ti – PZ T0), ΔNZ= (NZ Ti – NZ T0) and ΔΔ = ΔPZ – ΔNZ. An expected effect of the product corresponds to a ΔΔ on D56 compared to baseline ≥ 0.1 for the L* parameter and ≥ 1 for the ITA° parameter. Δ from D28 to D0, and from D56 to D0 were compared between zones using paired Student’s t-test.
Figure 2
Figure 2
Skin acceptability of the product after 2 months of application.
See this image and copyright information in PMC

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