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. 1985 Aug;99(4):756-9.
doi: 10.1037//0735-7044.99.4.756.

Exposure to a cat produces opioid analgesia in rats

L S Lester, M S Fanselow

Exposure to a cat produces opioid analgesia in rats

L S Lester et al. Behav Neurosci. 1985 Aug.

Abstract

Two experiments were conducted to test the prediction that rats should react with reduced sensitivity/reactivity to nociceptive stimulation in the presence of a cat. In Experiment 1, naloxone or saline was administered, and rats were exposed to no stimulus, a novel stimulus, or a cat. In Experiment 2, rats were exposed to either no stimulus or a cat, and naltrexone was administered. In both experiments, rats tested in the presence of the cat showed a significant reduction in sensitivity/reactivity to a skin-irritating formalin injection. Naltrexone reversed this analgesia.

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