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Review
. 2024 Apr;121(4):264-271.
doi: 10.1007/s00347-024-01995-w. Epub 2024 Mar 4.

[Bacterial endogenous endophthalmitis : Spectrum of pathogens and drug therapy]

[Article in German]
Thomas Ness  1   2
Affiliations
Review

[Bacterial endogenous endophthalmitis : Spectrum of pathogens and drug therapy]

[Article in German]
Thomas Ness. Ophthalmologie. 2024 Apr.

Abstract
in English, German

Endogenous endophthalmitis represents an ophthalmological emergency requiring immediate diagnostics and treatment. Pathogens should be detected using appropriate methods, such as the Freiburg endophthalmitis set. In bacterial endophthalmitis both Gram-positive and Gram-negative bacteria can be detected. Frequent underlying sources include endocarditis, gastrointestinal or urogenital surgery, indwelling venous catheters, liver abscesses, skin or soft tissue infections, meningitis or less commonly, intravenous drug abuse. The treatment consists of systemic and intraocular administration of antibiotics and vitrectomy. Systemic or intraocular corticosteroids can additionally be considered.

Eine endogene Endophthalmitis stellt einen ophthalmologischen Notfall dar, der umgehender Diagnostik und Therapie bedarf. Es sollte mit geeigneten Methoden, wie beispielsweise dem Freiburger Endophthalmitis-Set, ein Keimnachweis erfolgen. Bei der bakteriellen endogenen Endophthalmitis sind sowohl grampositive als auch gramnegative Keime nachweisbar. Häufige Quellen sind eine Endokarditis, ein gastrointestinaler oder urogenitaler Eingriff, ein venöser Venenverweilkatheter, ein Leberabszess, eine Haut- oder Weichteilinfektion, eine Meningitis oder seltener ein intravenöser Drogenabusus. Die Therapie besteht aus einer systemischen und intraokularen Gabe von Antibiotika und einer Vitrektomie. Systemische oder intraokulare Kortikosteroide können zusätzlich erwogen werden.

Keywords: Antibiotics; Eye infection; Ophthalmological emergency; Sepsis; Vitrectomy.

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References

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