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. 2024 Mar 4;16(1):e12558.
doi: 10.1002/dad2.12558. eCollection 2024 Jan-Mar.

Impact of mindfulness-based and health self-management interventions on mindfulness, self-compassion, and physical activity in older adults with subjective cognitive decline: A secondary analysis of the SCD-Well randomized controlled trial

Ylenia D'elia  1 , Tim Whitfield  2 , Marco Schlosser  2   3 , Antoine Lutz  4 , Thorsten Barnhofer  5 , Gaël Chételat  6 , Natalie L Marchant  2 , Julie Gonneaud  6 , Olga Klimecki  3   7 ; Medit‐Ageing group
Collaborators, Affiliations

Impact of mindfulness-based and health self-management interventions on mindfulness, self-compassion, and physical activity in older adults with subjective cognitive decline: A secondary analysis of the SCD-Well randomized controlled trial

Ylenia D'elia et al. Alzheimers Dement (Amst). .

Abstract

Introduction: Older adults experiencing subjective cognitive decline (SCD) have a higher risk of dementia. Reducing this risk through behavioral interventions, which can increase emotional well-being (mindfulness and compassion) and physical activity, is crucial in SCD.

Methods: SCD-Well is a multicenter, observer-blind, randomized, controlled, superiority trial. Three hundred forty-seven participants (mean [standard deviation] age: 72.7 [6.9] years; 64.6% women) were recruited from memory clinics in four European sites to assess the impact of an 8-week caring mindfulness-based approach for seniors (CMBAS) and a health self-management program (HSMP) on mindfulness, self-compassion, and physical activity.

Results: CMBAS showed a significant within-group increase in self-compassion from baseline to post-intervention and both a within- and between-group increase to follow-up visit (24 weeks). HSMP showed a significant within- and between-group increase in physical activity from baseline to post-intervention and to follow-up visit.

Discussion: Non-pharmacological interventions can differentially promote modifiable factors linked to healthy aging in older adults with SCD.

Keywords: Alzheimer's disease; aging; dementia; mindfulness; non‐pharmacological interventions; physical activity; self‐compassion.

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Conflict of interest statement

T.B. has received honoraria for workshops on MBI and is the co‐author of a book on mindfulness‐based cognitive therapy published by Guilford Press. O.K. received honoraria for research, training, and consulting related to meditation. All the other authors, Y.D., T.W., M.S., A.L., G.C., N.L.M., and J.G., have no conflicts to declare. Author disclosures are available in the supporting information.

Figures

FIGURE 1
FIGURE 1
Consort flow diagram of enrolment and randomization to CMBAS and HSMP interventions. CMBAS, caring mindfulness‐based approach for seniors; HSMP, health self‐management program.
FIGURE 2
FIGURE 2
This data‐based plot shows the evolution of average self‐compassion scores from baseline (V1) to post‐intervention (V2) and follow‐up (V3) for each intervention condition. The y axis represents the mean score on the SCS‐SF questionnaire from 20 to 60 (observed range in SCD‐Well: 37 to 41). V1, baseline visit; V2, post‐intervention visit after 8 weeks; V3, follow‐up visit 24 weeks post‐intervention. Asterisk corresponds to between‐group significance. * P < 0.05. CMBAS, caring mindfulness‐based approach for seniors; HSMP, health self‐management program; SCS‐SF, Self‐Compassion Scale–Short Form.
FIGURE 3
FIGURE 3
This data‐based plot shows the evolution of average physical activity scores from baseline (V1) to post‐intervention (V2) and follow‐up (V3) for each intervention condition. The y axis represents the mean score on the PASE questionnaire from 20 to 200 to allow for a better visualization (maximum range: from 0 to 793, observed range in SCD‐Well: 117 to 141. V1, baseline visit; V2, post‐intervention visit after 8 weeks; V3, follow‐up visit 24 weeks post‐intervention. Asterisks correspond to between‐group significance. * P < 0.05. CMBAS, caring mindfulness‐based approach for seniors; HSMP, health self‐management program; PASE, Physical Activity Scale for the Elderly.
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