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. 2024 Feb;76(1):878-885.
doi: 10.1007/s12070-023-04304-0. Epub 2023 Nov 17.

Impact on Hearing Among SARS COV-2 Infected Adults and Children Born to Gestational COVID-19 Infected Mothers: A Prospective Case Control Study

Balaji Swaminathan  1 , Jhansirani Vidyasagar  1   2 , Shanmugam Vellavedu Umapathy  1 , Ruta Shanmugam  1 , Prakash Paramasivam Gunasekaran  1 , Lavanya Varadhan Mani  1 , Sangeetha Murugan  1
Affiliations

Impact on Hearing Among SARS COV-2 Infected Adults and Children Born to Gestational COVID-19 Infected Mothers: A Prospective Case Control Study

Balaji Swaminathan et al. Indian J Otolaryngol Head Neck Surg. 2024 Feb.

Abstract

SARS COV 2 infection affects primarily the respiratory system and various organs in humans is responsible for higher mortality secondary to cytokine storm during the COVID-19 pandemic. It affects the internal auditory system is responsible for Sensory neural hearing loss in adults as well as children born to COVID-19 infected mothers. This study was aimed to detect the pattern of hearing loss in COVID-19 infected adults and pattern of hearing loss in children born to gestational COVID-19 infected mothers. Fifty asymptomatic RT-PCR COVID-19 infected adults and age, sex matched healthy controls were evaluated for audiological profile using Pure Tone Audiometry (PTA). Children born to COVID-19 infected mothers were tested using Transient product otoacoustic emissions and click-evoked auditory brainstem responses (ABRs) compared with children born to non-COVID mothers. PTA auditory profile of COVID-19 infected adults on day 7 had 30% (16 out of 50) significant high frequency sensory neural hearing impairment for 4000 Hz (p value 0.003), 6000 Hz (p value 0.001), 8000 Hz (p value 0.001). Repeat PTA testing on day 30 showed normal hearing. Whereas in children, 40% (n = 20) born to COVID-19 infected mothers had OAE as "Refer". BERA (ABRs) testing of that OAE "Refer" children revealed 30% (n = 6) hearing impairment. COVID-19 infection cause transient type of high frequency sensory neural hearing loss in adults. Whereas in children born to COVID-19 infected mothers there is risk of developing permanent, progressive or long-standing transient type of sensory neural hearing loss.

Keywords: Deafness; Gestational COVID-19; Hearing loss; SARS COVID-19.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Audiological evaluation of adults infected with SARS COVID-19 using Pure tone audiometry test
Fig. 2
Fig. 2
Pure tone audiometry results of left ear among COVID-19 infected adults (study group) and controls
Fig. 3
Fig. 3
Pure tone audiometry results of Right ear among COVID-19 infected adults (study group) and controls
Fig. 4
Fig. 4
Audiological evaluation OAE in children born to COVID-19 infected mothers during pregnancy
Fig. 5
Fig. 5
Bar chart showing distribution according to the results of first screening of the both ears with OAE-1
Fig. 6
Fig. 6
Bar chart showing distribution according to the results of second screening of the both ears with OAE-2
Fig. 7
Fig. 7
Bar chart showing distribution according to the results of BERA between the groups
Fig. 8
Fig. 8
OAE results of a child born to COVID-19 infected mother
Fig. 9
Fig. 9
Distribution of BERA positivity among and OAE positive children in the study group analysing children born to COVID-19 infected mothers
See this image and copyright information in PMC

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References

    1. Jafari Z, Kolb BE, Mohajerani MH. Hearing loss, tinnitus, and dizziness in COVID-19: a systematic review and meta-analysis. Can J Neurol Sci. 2022;49(2):184–195. doi: 10.1017/cjn.2021.63. - DOI - PMC - PubMed
    1. Lechien JR, Chiesa-Estomba CM, De Siati DR. Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. Eur Arch Otorhinolaryngol. 2020;277(8):2251–2261. doi: 10.1007/s00405-020-05965-1. - DOI - PMC - PubMed
    1. Mao L, Jin H, Wang M. Neurologic manifestations of hospitalized patients with Coronavirus disease 2019 in Wuhan China. JAMA Neurol. 2020;77(6):683–690. doi: 10.1001/jamaneurol.2020.1127. - DOI - PMC - PubMed
    1. Wichmann D, Sperhake JP, Lütgehetmann M, Steurer S, Edler C, Heinemann A, et al. Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study. Ann Intern Med. 2020;173(4):268–277. doi: 10.7326/M20-2003. - DOI - PMC - PubMed
    1. Jeong J, Choi HS. Sudden sensorineural hearing loss after COVID-19 vaccination. Int J Infect Dis. 2021;113:341–343. doi: 10.1016/j.ijid.2021.10.025. - DOI - PMC - PubMed

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