A Clinical Study of Malignant Sino-Nasal Tumors

Abstract

The sino-nasal cavities represent an anatomical region affected by a variety of tumors with clinical, etiological, genetic and pathological features, which are distinct from tumors commonly encountered in the area of head and neck cancers. We have undertaken this study with the aim of assessing clinical profile, various treatment modalities and outcome of patients with malignant sino-nasal tumors. In this prospective study of two years, done in a rural tertiary care hospital of India, 40 patients with malignant neoplastic tumors of nasal cavity, sinuses and nasopharynx were analyzed for their clinic-pathological and radiological profile and surgical management. The age range found was 10-78 years. There was a significant male preponderance with 23 (57.5%) male patients. Most common histological type seen in our study was Squamous cell carcinoma amongst 32 (80%) of cases. Maximum number of patients were managed with combination therapy of Surgery and Radiotherapy i.e. in 21 patients (52.5%). Multimodality treatment has been deemed the most efficacious choice of treatment which would improve disease free survival for the patients.

Keywords: Malignant neoplasm; Sino-nasal tumors.

Fig. 1

Presenting complaints among patients

Fig. 2

Image of patient presenting with right cheek swelling, Firm to hard in consistency

Fig. 3

Sublabial approach as a part of combined approach for tumour removal showing right nasal mass

Fig. 4

Endoscopic view post tumour resection, dura covered with fascia lata

Fig. 5

Endoscopic resection of tumour in right nasal cavity piecemeal

Fig. 6

Axial cuts of CT scan of rhabdomyosarcoma patient showing infratemporal and nasopharyngeal extension