Metastasizing Pleomorphic Adenoma of Parotid Gland: A Case Report and Literature Review

doi:10.1007/s12070-023-04154-w

. 2024 Feb;76(1):1123-1125.

doi: 10.1007/s12070-023-04154-w. Epub 2023 Sep 4.

Metastasizing Pleomorphic Adenoma of Parotid Gland: A Case Report and Literature Review

Lisa Catarzi^#¹, Guido Gabriele^#¹, Beatrice Pulli¹, Flavia Cascino², Paolo Gennaro¹

Affiliations

¹ Department of Maxillofacial Surgery, University of Siena, Siena, Italy.
² Department of Maxillofacial Surgery, Azienda Ospedaliero Universitaria Senese, Siena, Italy.

^# Contributed equally.

PMID: 38440507
PMCID: PMC10908766
DOI: 10.1007/s12070-023-04154-w

Metastasizing Pleomorphic Adenoma of Parotid Gland: A Case Report and Literature Review

Lisa Catarzi et al. Indian J Otolaryngol Head Neck Surg. 2024 Feb.

. 2024 Feb;76(1):1123-1125.

doi: 10.1007/s12070-023-04154-w. Epub 2023 Sep 4.

Authors

Lisa Catarzi^#¹, Guido Gabriele^#¹, Beatrice Pulli¹, Flavia Cascino², Paolo Gennaro¹

Affiliations

¹ Department of Maxillofacial Surgery, University of Siena, Siena, Italy.
² Department of Maxillofacial Surgery, Azienda Ospedaliero Universitaria Senese, Siena, Italy.

^# Contributed equally.

PMID: 38440507
PMCID: PMC10908766
DOI: 10.1007/s12070-023-04154-w

Abstract

The authors hereby present a case report of metastasizing pleomorphic adenoma (MPA) of the parotid gland with multiple metachronous cervical lymph node metastases and sternocleidomastoid muscle infiltration. Diagnostic evaluation, surgical management, and follow-up are discussed along with a brief review of the literature.

Keywords: Metastasizing pleomorphic adenoma; Metastasizing salivary gland tumor; Parotid gland tumor.

© Association of Otolaryngologists of India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Conflict of interest statement

Competing Interests and FundingThe authors have no competing interests to declare that are relevant to the content of this article. The authors did not receive support from any organization for the submitted work. The authors declare they have no financial interests.

Figures

**Fig. 1**
MRI scan (A) axial view: showing multinodular relapse of pleomorphic adenoma of the left parotid gland; (B) coronal view: showing nodules near the upper and lower pole of the left parotid gland and multiple nodules in touch with an anterior and superficial margin of the sternocleidomastoid muscle

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References

1. Reiland MD, Koutlas IG, Gopalakrishnan R, Pearson AG, Basi DL. Metastasizing pleomorphic adenoma presents intraorally: a case report and review of the literature. J Oral Maxillofac Surg. 2012;70(10):e531–e540. doi: 10.1016/j.joms.2012.06.185. - DOI - PubMed
1. Nouraei SA, Ferguson MS, Clarke PM, et al. Metastasizing pleomorphic salivary adenoma. Arch Otolaryngol Head Neck Surg. 2006;132(7):788–793. doi: 10.1001/archotol.132.7.788. - DOI - PubMed
1. Gnepp DR. Tumours of the salivary glands. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organisation classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. pp. 245–246.
1. Knight J, Ratnasingham K. Metastasising pleomorphic adenoma: systematic review. Int J Surg. 2015;19:137–145. doi: 10.1016/j.ijsu.2015.04.084. - DOI - PubMed
1. Chen Ih Tu. Pleomorphic adenoma of the parotid gland metastasizing to the cervical lymph node. Otolaryngol Head Neck Surg. 2000;122(3):455–457. doi: 10.1016/S0194-5998(00)70064-7. - DOI - PubMed

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[1] Reiland MD, Koutlas IG, Gopalakrishnan R, Pearson AG, Basi DL. Metastasizing pleomorphic adenoma presents intraorally: a case report and review of the literature. J Oral Maxillofac Surg. 2012;70(10):e531–e540. doi: 10.1016/j.joms.2012.06.185. - DOI - PubMed

[2] Reiland MD, Koutlas IG, Gopalakrishnan R, Pearson AG, Basi DL. Metastasizing pleomorphic adenoma presents intraorally: a case report and review of the literature. J Oral Maxillofac Surg. 2012;70(10):e531–e540. doi: 10.1016/j.joms.2012.06.185. - DOI - PubMed

[3] Nouraei SA, Ferguson MS, Clarke PM, et al. Metastasizing pleomorphic salivary adenoma. Arch Otolaryngol Head Neck Surg. 2006;132(7):788–793. doi: 10.1001/archotol.132.7.788. - DOI - PubMed

[4] Nouraei SA, Ferguson MS, Clarke PM, et al. Metastasizing pleomorphic salivary adenoma. Arch Otolaryngol Head Neck Surg. 2006;132(7):788–793. doi: 10.1001/archotol.132.7.788. - DOI - PubMed

[5] Gnepp DR. Tumours of the salivary glands. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organisation classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. pp. 245–246.

[6] Gnepp DR. Tumours of the salivary glands. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organisation classification of tumours: pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. pp. 245–246.

[7] Knight J, Ratnasingham K. Metastasising pleomorphic adenoma: systematic review. Int J Surg. 2015;19:137–145. doi: 10.1016/j.ijsu.2015.04.084. - DOI - PubMed

[8] Knight J, Ratnasingham K. Metastasising pleomorphic adenoma: systematic review. Int J Surg. 2015;19:137–145. doi: 10.1016/j.ijsu.2015.04.084. - DOI - PubMed

[9] Chen Ih Tu. Pleomorphic adenoma of the parotid gland metastasizing to the cervical lymph node. Otolaryngol Head Neck Surg. 2000;122(3):455–457. doi: 10.1016/S0194-5998(00)70064-7. - DOI - PubMed

[10] Chen Ih Tu. Pleomorphic adenoma of the parotid gland metastasizing to the cervical lymph node. Otolaryngol Head Neck Surg. 2000;122(3):455–457. doi: 10.1016/S0194-5998(00)70064-7. - DOI - PubMed

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Metastasizing Pleomorphic Adenoma of Parotid Gland: A Case Report and Literature Review

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Metastasizing Pleomorphic Adenoma of Parotid Gland: A Case Report and Literature Review

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