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. 2024 Feb;76(1):1275-1278.
doi: 10.1007/s12070-023-04266-3. Epub 2023 Oct 19.

A Googly in the Neck-Castleman Disease

Affiliations

A Googly in the Neck-Castleman Disease

Ritu K Sheth et al. Indian J Otolaryngol Head Neck Surg. 2024 Feb.

Abstract

Lymphoproliferative disorders comprise of a group of heterogenous diseases characterised by uncontrolled production of lymphocytes.Castleman disease (CD) is one such disease and comprises of a group of rare disorders that involve enlarged lymph nodes and a broad range of inflammatory symptoms and laboratory abnormalities [1]. We came across young girl who presented to us in the out patient department with this disease After ruling out other pathologies and confirming the diagnosis by doing a tissue biopsy the girl was treated surgically and is disease free till date.

Keywords: Neck mass; Paediatric Castleman disease; Unicentric CD.

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Conflict of interest statement

Conflict of interestNo conflict of interest between authors.

Figures

Image 1
Image 1
Section from lymph node showing involution of germinal centres and onion skin appearance of mantle zone.
Image 2
Image 2
CT Scan (plain) Of neck showing Cervical lymph node enlargement
Image 3
Image 3
Photographic image of neck showing the lymph nodal enlargement and scar of open biopsy
Image 4
Image 4
Showing specimen

References

    1. https://cdcn.org/castleman-disease/overview/
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    1. Keller, A. R., Hochholzer, L. & Castleman, B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 29, 670–683 (1972). - PubMed
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