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. 2024 Feb;18(3):103-113.
doi: 10.2217/bmm-2023-0682. Epub 2024 Mar 5.

C-reactive protein to albumin ratio may predict in-hospital mortality in non-ST elevation myocardial infarction

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C-reactive protein to albumin ratio may predict in-hospital mortality in non-ST elevation myocardial infarction

Tuğba S Menekşe et al. Biomark Med. 2024 Feb.

Abstract

Objective: The authors investigated the value of novel inflammatory markers, systemic immune-inflammation index and C-reactive protein to albumin ratio (CAR), to predict in-hospital mortality in patients with non-ST elevation myocardial infarction (NSTEMI). Materials & methods: A total of 308 patients who underwent percutaneous coronary intervention because of NSTEMI were retrospectively included in the study. Killip classification, Thrombolysis in Myocardial Infarction score, SYNTAX score, and CAR and systemic immune-inflammation index values were calculated. Results: CAR (cutoff: 0.0864; sensitivity: 94.1%; specificity: 40.5%; p = 0.008) and Killip classification (cutoff: 2.5; sensitivity: 64.7%; specificity: 8.9%; p = 0.001) were found to be significantly higher in determining in-hospital mortality. Conclusion: This study revealed that CAR is an inexpensive and significant factor in predicting in-hospital mortality in patients undergoing percutaneous coronary intervention for NSTEMI.

Keywords: C-reactive protein to albumin ratio; Killip; NSTEMI; in-hospital mortality; systemic immune-inflammation index.

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Conflict of interest statement

The authors have no competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending or royalties.

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