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Case Reports
. 2024 Mar 4;17(3):e259653.
doi: 10.1136/bcr-2024-259653.

Squamous cell carcinoma of breast metastasising to upper lip

Affiliations
Case Reports

Squamous cell carcinoma of breast metastasising to upper lip

Amitabh Kumar Upadhyay et al. BMJ Case Rep. .

Abstract

Breast cancer is a heterogeneous set of carcinomas comprising a subgroup of invasive ductal carcinomas and numerous infrequent subtypes. Primary squamous cell carcinoma (SCC) breast is sporadic, accounting for less than 0.1% of all invasive subtypes. Primary metastases to soft tissues of the oral cavity are incredibly rare, amounting to 0.1% of oral malignancies. Diagnosing metastasis to the oral cavity is an enigma to clinicians without pathognomonic signs and symptoms. Here, we report a case of SCC breast, who developed metastatic deposits in the left upper lip after a disease-free survival of 1 year. There are no reports of SCC breast metastasising to the oral cavity, and probably, this is the first such case getting reported. The survival of such patients is abysmal, with most cases surviving less than a year post diagnosis. While treating patients with a history of malignancy, a high degree of clinical presentiment is required.

Keywords: Breast cancer; Chemotherapy; Head and neck cancer; Oncology.

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Conflict of interest statement

Competing interests: None declared.

References

    1. Xu Y, Gong M, Wang Y, et al. . Global trends and forecasts of breast cancer incidence and deaths. Sci Data 2023;10. 10.1038/s41597-023-02253-5 - DOI - PMC - PubMed
    1. Sung H, Ferlay J, Siegel RL, et al. . Global cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021;71:209–49. 10.3322/caac.21660 - DOI - PubMed
    1. Makki J. Diversity of breast carcinoma: histological subtypes and clinical relevance. Clin Med Insights Pathol 2015;8:23–31. 10.4137/CPath.S31563 - DOI - PMC - PubMed
    1. Ramamoorthy S, Thankappan P, Tharmasahayam IJ, et al. . Stephen EA.Triple negative invasive Ductal carcinoma of breast with oral metastasis: A case Reportj Clin of Diagn. 2023;17. 10.7860/JCDR/2023/61996/17951 - DOI
    1. Chikarmane SA, Tirumani SH, Howard SA, et al. . Metastatic patterns of breast cancer subtypes: what Radiologists should know in the era of personalized cancer medicine. Clin Radiol 2015;70:1–10. 10.1016/j.crad.2014.08.015 - DOI - PubMed

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