Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May 31;195(2):1114-1116.
doi: 10.1093/plphys/kiae132.

Two auxins are better than one: BiAux joins forces with auxin to enhance lateral root formation

Héctor H Torres-Martínez  1   2
Affiliations

Two auxins are better than one: BiAux joins forces with auxin to enhance lateral root formation

Héctor H Torres-Martínez. Plant Physiol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement. The author declares that there is no conflict of interest.

Figures

Figure.
Figure.
A proposed model for BiAux action mechanism in LR formation. The traditional model for auxin signal transduction explains that auxin works as a molecular glue that promotes co-receptor assembly between TIR/AFB and Aux/IAA protein family members. In this new research piece, González-García et al. (2024) described the isolation and characterization of a new metabolite, BiAux, which is accumulated when roots are grown under illumination, such as on traditional Petri dishes. It was demonstrated that BiAux binds to a specific TIR1 site close to the auxin binding site, and the binding seems to stabilize the co-receptor complex. Specifically, simultaneous treatment with auxin and BiAux enhanced the co-receptor formation between TIR1 or AFB2 and IAA18 or IAA28, auxin signal regulators for early LR formation. These complexes might release the positive auxin signal regulator ARF7, which was found to mediate the BiAux response during the lateral formation process. Figure was created with BioRender.com by H.H.T.M.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Du Y, Scheres B. Lateral root formation and the multiple roles of auxin. J Exp Bot. 2018:69(2):155–167. 10.1093/jxb/erx223 - DOI - PubMed
    1. Gagne JM, Downes BP, Shiu S-H, Durski AM, Vierstra RD. The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc Natl Acad Sci U S A. 2002:99(17):11519–11524. 10.1073/pnas.162339999 - DOI - PMC - PubMed
    1. González-García MP, Sáez A, Lanza M, Hoyos P, Bustillo-Avendaño E, Pacios LF, Gradillas A, Moreno-Risueno MA, Hernaiz MJ, del Pozo JC, et al. Synthetically derived BiAux modulates auxin co-receptor activity to stimulate lateral root formation. Plant Physiol. 2024;195(2):1694–1711. 10.1093/plphys/kiae090 - DOI - PMC - PubMed
    1. Manzano C, Ramirez-Parra E, Casimiro I, Otero S, Desvoyes B, De Rybel B, Beeckman T, Casero P, Gutierrez C, del Pozo JC. Auxin and epigenetic regulation of SKP2B, an F-box that represses lateral root formation. Plant Physiol. 2012:160(2):749–762. 10.1104/pp.112.198341. - DOI - PMC - PubMed
    1. Remington DL, Vision TJ, Guilfoyle TJ, Reed JW. Contrasting modes of diversification in the Aux/IAA and ARF gene families. Plant Physiol. 2004:135(3):1738–1752. 10.1104/pp.104.039669 - DOI - PMC - PubMed

MeSH terms