Pulmonary Interstitial Macrophages stIMulate Regulatory T-Cell Responses

Affiliations

¹ Department of Medicine University of North Carolina School of Medicine Chapel Hill, North Carolina.
² Department of Pediatrics University of North Carolina School of Medicine Chapel Hill, North Carolina.

Editorial

Stephen A Schworer et al. Am J Respir Cell Mol Biol. 2024 Jun.

. 2024 Jun;70(6):429-430.

doi: 10.1165/rcmb.2024-0049ED.

¹ Department of Medicine University of North Carolina School of Medicine Chapel Hill, North Carolina.
² Department of Pediatrics University of North Carolina School of Medicine Chapel Hill, North Carolina.

No abstract available

Comment on

Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3⁺ Regulatory T Cells.
Legrand C, Vanneste D, Hego A, Sabatel C, Mollers K, Schyns J, Maréchal P, Abinet J, Tytgat A, Liégeois M, Polese B, Meunier M, Radermecker C, Fiévez L, Bureau F, Marichal T. Legrand C, et al. Am J Respir Cell Mol Biol. 2024 Jun;70(6):446-456. doi: 10.1165/rcmb.2023-0254OC. Am J Respir Cell Mol Biol. 2024. PMID: 38329817

1. Lambrecht BN, Hammad H. Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu Rev Immunol . 2012;30:243–270. - PubMed
1. Kawasaki T, Ikegawa M, Kawai T. Antigen presentation in the lung. Front Immunol . 2022;13:860915. - PMC - PubMed
1. Aegerter H, Lambrecht BN, Jakubzick CV. Biology of lung macrophages in health and disease. Immunity . 2022;55:1564–1580. - PMC - PubMed
1. Hussell T, Bell TJ. Alveolar macrophages: plasticity in a tissue-specific context. Nat Rev Immunol . 2014;14:81–93. - PubMed
1. Coleman MM, Ruane D, Moran B, Dunne PJ, Keane J, Mills KH. Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cells. Am J Respir Cell Mol Biol . 2013;48:773–780. - PubMed