Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Mar 6;43(1):39.
doi: 10.1186/s41043-024-00526-2.

Epidemiologic analysis of antimicrobial resistance in hospital departments in China from 2022 to 2023

Hui-Jun Bai #  1 , Qing-Feng Geng #  2 , Fang Jin #  3 , Yong-Li Yang #  4
Affiliations

Epidemiologic analysis of antimicrobial resistance in hospital departments in China from 2022 to 2023

Hui-Jun Bai et al. J Health Popul Nutr. .

Abstract

Bacterial drug resistance monitoring in hospitals is a crucial aspect of healthcare management and a growing concern worldwide. In this study, we analysed the bacterial drug resistance surveillance in our hospital from 2022 Q1 to 2023 Q2. The main sampling sources were respiratory, blood, and urine-based, and the main clinical infections were respiratory and genitourinary in nature. Specimens were inoculated and cultured; bacterial strains were isolated using a VITEK® 2 Compact 60-card automatic microorganism identifier (bioMerieux, Paris, France) and their matching identification cards were identified, and manual tests were supplemented for strain identification. The most common Gram-positive bacteria detected were Staphylococcus aureus, followed by Enterococcus faecalis (E. faecalis), Staphylococcus epidermidis (S. epidermidis), and Staphylococcus haemolyticus (S. haemolyticus). The most common Gram-negative bacteria detected were Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The most prevalent multidrug-resistant bacteria were those producing extended-spectrum beta-lactamases, followed by methicillin-resistant Staphylococcus aureus, followed by carbapenem-resistant Enterobacterales. This study suggests that the prevention and control of infections in the respiratory and genitourinary systems should be the focus of anti-infective work and that the use of antimicrobials should be reduced and regulated to prevent the emergence and spread of resistant bacteria.

Keywords: Antimicrobial susceptibility testing; Bacterial drug resistance surveillance; Hospital infections; Multidrug-resistant bacteria; Penicillin.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Trend in the number of multi-drug resistant bacteria detected from 2022Q1 to 2023Q2
Fig. 2
Fig. 2
Trend in the number of multi-drug resistant bacteria detected in four types of samples from 2022Q1 to 2023Q2
Fig. 3
Fig. 3
The distribution of resisted drug against Pseudomonas aeruginosa and Acinetobacter baumannii.  A The resistance rate of Pseudomonas aeruginosa against multiple drugs.  B The resistance rate of Acinetobacter baumannii against multiple drugs
See this image and copyright information in PMC

References

    1. World Health Organization. Report signals increasing resistance to antibiotics in bacterial infections in humans and need for better data. 9. December 2022, https://www.who.int/news/item/09-12-2022-report-signals-increasing-resis....
    1. World Health Organization. Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report: 2021. 9 June 2021, https://www.who.int/publications/i/item/9789240027336.
    1. Kern WV, Rieg S. Burden of bacterial bloodstream infection-a brief update on epidemiology and significance of multidrug-resistant pathogens. Clin Microbiol Infect. 2020;26(2):151–7. doi: 10.1016/j.cmi.2019.10.031. - DOI - PubMed
    1. Martinez M, Silley P. Antimicrobial drug resistance. Handb Exp Pharmacol. 2010;199:227–64. doi: 10.1007/978-3-642-10324-7_10. - DOI - PubMed
    1. Davies J, Davies D. Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev. 2010;74(3):417–33. doi: 10.1128/MMBR.00016-10. - DOI - PMC - PubMed

MeSH terms

Substances