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Review
. 2024 Feb 21:11:1325559.
doi: 10.3389/fvets.2024.1325559. eCollection 2024.

Trends of regenerative tissue engineering for oral and maxillofacial reconstruction in veterinary medicine

Steven Dwi Purbantoro  1   2 , Teeanutree Taephatthanasagon  1   2 , Medania Purwaningrum  1   2   3 , Thanyathorn Hirankanokchot  1 , Santiago Peralta  4 , Nadine Fiani  4 , Chenphop Sawangmake  1   2   5   6 , Sirirat Rattanapuchpong  1   2   7
Affiliations
Review

Trends of regenerative tissue engineering for oral and maxillofacial reconstruction in veterinary medicine

Steven Dwi Purbantoro et al. Front Vet Sci. .

Abstract

Oral and maxillofacial (OMF) defects are not limited to humans and are often encountered in other species. Reconstructing significant tissue defects requires an excellent strategy for efficient and cost-effective treatment. In this regard, tissue engineering comprising stem cells, scaffolds, and signaling molecules is emerging as an innovative approach to treating OMF defects in veterinary patients. This review presents a comprehensive overview of OMF defects and tissue engineering principles to establish proper treatment and achieve both hard and soft tissue regeneration in veterinary practice. Moreover, bench-to-bedside future opportunities and challenges of tissue engineering usage are also addressed in this literature review.

Keywords: maxillofacial regeneration; oral and maxillofacial defects; oral and maxillofacial reconstruction; tissue engineering; veterinary.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

Figures

Figure 1
Figure 1
Translational concept of oral and maxillofacial tissue engineering in veterinary medicine.
Figure 2
Figure 2
Future challenges of oral and maxillofacial tissue engineering in veterinary medicine.
See this image and copyright information in PMC

References

    1. Winer JN, Verstraete FJ, Cissell DD, Lucero S, Athanasiou KA, Arzi B. The application of 3-dimensional printing for preoperative planning in oral and maxillofacial surgery in dogs and cats. Vet Surg. (2017) 46:942–51. 10.1111/vsu.12683 - DOI - PubMed
    1. Langer R, Vacanti JP. Tissue engineering. Science. (1993) 260:920–6. 10.1126/science.8493529 - DOI - PubMed
    1. Krafts KP. Tissue repair: the hidden drama. Organogenesis. (2010) 6:225–33. 10.4161/org.6.4.12555 - DOI - PMC - PubMed
    1. Fertala J, Wang ML, Rivlin M, Beredjiklian PK, Abboud J, Arnold WV, et al. . Extracellular targets to reduce excessive scarring in response to tissue injury. Biomolecules. (2023) 13:758. 10.3390/biom13050758 - DOI - PMC - PubMed
    1. Oakes S, Kumar V, Abbas A, Aster J. Inflammation and Repair. Robbins and Cotran's Pathologic Basis of Disease. 10th ed. Amsterdam: Elsevier; (2020). p. 75–6.

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