Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Apr 11;13(4):e0124623.
doi: 10.1128/mra.01246-23. Epub 2024 Mar 7.

Complete genome sequence of Bacillus halotolerans F29-3, a fengycin-producing strain

Hung-Yu Shu #  1 , Chien-Chi Chen #  2 , Hsin-Tzu Ku  1 , Chun-Lin Wang  2 , Keh-Ming Wu  3 , Hui-Ying Weng  4 , Shih-Tung Liu  5 , Chyi-Liang Chen  5   6 , Cheng-Hsun Chiu  6   7
Affiliations

Complete genome sequence of Bacillus halotolerans F29-3, a fengycin-producing strain

Hung-Yu Shu et al. Microbiol Resour Announc. .

Abstract

Bacillus halotolerans F29-3, a Gram-positive bacterium, is recognized for its synthesis of the antifungal substance fengycin. This announcement introduces the complete genome sequence and provides insights into the genetic products related to antibiotic secondary metabolites, including non-ribosomal peptide synthetase (NRPS), polyketide synthase (PKS), and NRPS/PKS combination.

Keywords: Bacillus halotolerans; Bacillus subtilis; fengycin; non-ribosomal peptide synthetase; polyketide synthase.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig 1
Fig 1
A phylogenetic tree of the F29-3 strain’s genome was generated using the TYGS (accessed on 26 November 2023). The lengths of the branches in the tree are proportional to the Genome BLAST Distance Phylogeny (GBDP) distance formula d5. The numerical values displayed along the branches represent the GBDP pseudobootstrap support values, all exceeding 60% out of 100 replications, with an average branch support of 85.8%.
See this image and copyright information in PMC

References

    1. Meier-Kolthoff JP, Carbasse JS, Peinado-Olarte RL, Göker M. 2022. TYGS and LPSN: a database tandem for fast and reliable genome-based classification and nomenclature of prokaryotes. Nucleic Acids Res 50:D801–D807. doi:10.1093/nar/gkab902 - DOI - PMC - PubMed
    1. Vanittanakom N, Loeffler W, Koch U, Jung G. 1986. Fengycin- a novel antifungal lipopeptide antibiotic produced by Bacillus subtilis F29-3. J Antibiot (Tokyo) 39:888–901. doi:10.7164/antibiotics.39.888 - DOI - PubMed
    1. Chang LK, Chen CL, Chang YS, Tschen JSM, Chen YM, Liu ST. 1994. Construction of Tn917ac1, a transposon useful for mutagenesis and cloning of Bacillus subtilis genes. Gene 150:129–134. doi:10.1016/0378-1119(94)90871-0 - DOI - PubMed
    1. Chen CL, Chang LK, Chang YS, Liu ST, Tschen JSM. 1995. Transposon mutagenesis and cloning of the genes encoding the biosynthesis of fengycin. Mol Gen Genet 248:121–125. doi:10.1007/BF02190792 - DOI - PubMed
    1. Lin GH, Chen CL, Tschen JS, Tsay SS, Chang YS, Liu ST. 1998. Molecular cloning and characterization of fengycin synthetase gene fenB from Bacillus subtilis. J Bacteriol 180:1338–1341. doi:10.1128/JB.180.5.1338-1341.1998 - DOI - PMC - PubMed

LinkOut - more resources