Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Affiliations

¹ J Hazlehurst, Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom of Great Britain and Northern Ireland.
² B Khoo, Division of Medicine, UCL, London, United Kingdom of Great Britain and Northern Ireland.
³ C Lobato, Biomedical Sciences, University of Copenhagen, Kobenhavn, Denmark.
⁴ I Ilesanmi, Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom of Great Britain and Northern Ireland.
⁵ S Abbott, Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom of Great Britain and Northern Ireland.
⁶ T Chan, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
⁷ S Pillai, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.
⁸ K Maslin, School of Nursing and Midwifery, University of Plymouth, Plymouth, United Kingdom of Great Britain and Northern Ireland.
⁹ S Purkayastha, Surgery, Imperial College Healthcare NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.
¹⁰ B McGowan, Endocrinology, Guy's and St Thomas' Hospitals NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.
¹¹ R Andrews, Medical School, University of Exeter, Exeter, United Kingdom of Great Britain and Northern Ireland.
¹² T Tan, Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom of Great Britain and Northern Ireland.

PMID: 38451861
PMCID: PMC11046333
DOI: 10.1530/EC-23-0285

Review

Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Jonathan Hazlehurst et al. Endocr Connect. 2024.

. 2024 May 1;13(5):e230285.

doi: 10.1530/EC-23-0285. Epub 2024 Apr 1.

Authors

Affiliations

¹ J Hazlehurst, Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom of Great Britain and Northern Ireland.
² B Khoo, Division of Medicine, UCL, London, United Kingdom of Great Britain and Northern Ireland.
³ C Lobato, Biomedical Sciences, University of Copenhagen, Kobenhavn, Denmark.
⁴ I Ilesanmi, Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom of Great Britain and Northern Ireland.
⁵ S Abbott, Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom of Great Britain and Northern Ireland.
⁶ T Chan, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
⁷ S Pillai, Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Birmingham, United Kingdom of Great Britain and Northern Ireland.
⁸ K Maslin, School of Nursing and Midwifery, University of Plymouth, Plymouth, United Kingdom of Great Britain and Northern Ireland.
⁹ S Purkayastha, Surgery, Imperial College Healthcare NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.
¹⁰ B McGowan, Endocrinology, Guy's and St Thomas' Hospitals NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.
¹¹ R Andrews, Medical School, University of Exeter, Exeter, United Kingdom of Great Britain and Northern Ireland.
¹² T Tan, Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom of Great Britain and Northern Ireland.

PMID: 38451861
PMCID: PMC11046333
DOI: 10.1530/EC-23-0285

Abstract

Post bariatric hypoglycaemia (PBH) is typically a post-prandial hypoglycaemia occurring about 2-4 hours after eating in people who have undergone bariatric surgery. PBH develops relatively late after surgery and often after discharge from post-surgical follow-up by bariatric teams, leading to variability in diagnosis and management in non-specialist centres.

Aim: to improve and standardise clinical practice in the diagnosis and management of PBH.

Objectives: (1) to undertake an up-to-date review of the current literature; (2) to formulate practical and evidence-based guidance with regards on the diagnosis and treatment of PBH; (3) to recommend future avenues for research in this condition.

Method: A scoping review was undertaken after an extensive literature search. A consensus on the guidance and confidence in the recommendations was reached by the steering group authors prior to review by key stakeholders.

Outcome: We make pragmatic recommendations for the practical diagnosis and management of PBH including criteria for diagnosis and recognition, as well as recommendations for research areas that should be explored.

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Conflict of interest statement

T.M-M.T. declares that she is a shareholder in and consultant for Zihipp Ltd. B.K., C.B.L., G.A.B., R.A., S.P. and K.M. declare no conflicts of interest. S.A. declares consultancy fees for educational events from Johnson & Johnson. J.H. and K.McC. declare honoraria for speaking engagements and advisory work for Novo Nordisk. B.McG. declares that she is a shareholder in Reset Health, a research grant from Novo Nordisk, honoraria for advisory work for Novo Nordisk, Pfizer, Johnson & Johnson, Boehringer Ingleheim, and consultancy fees for educational events from Novo Nordisk, Lilly, Amgen, Astra Zeneca, Sanofi and Johnson & Johnson. S.F. collaborates with and receives funding from Novo Nordisk (Cell Therapy Programme). G.K.D. has received research grants from Novo Nordisk and DDM, as well as honoraria for lectures, presentations, speaker’s bureaus, manuscript writing and educational events from Novo Nordisk, Johnson & Johnson/Ethicon and Medtronic. R.L.B. reports honoraria from Novo Nordisk, Eli Lilly, Medscape, and ViiV Healthcare Ltd., and advisory board and consultancy work for Novo Nordisk, Eli Lilly, Pfizer, Gila Therapeutics Ltd., Epitomee Medical Ltd. and ViiV Healthcare Ltd., and from May 2023 is an employee and shareholder of Eli Lilly and Company.

Figures

**Figure 1**
Framework for diagnosis of post-bariatric hypoglycaemia and allied conditions.

See this image and copyright information in PMC

References

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Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Affiliations

Society for Endocrinology guidelines for the diagnosis and management of post-bariatric hypoglycaemia

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

References

Publication types

LinkOut - more resources

Full Text Sources