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. 2024 Mar 5;32(1):101223.
doi: 10.1016/j.omtm.2024.101223. eCollection 2024 Mar 14.

The very stable lentiviral vector

Gwendolyn K Binder  1 , Chien-Chung Chen  1
Affiliations

The very stable lentiviral vector

Gwendolyn K Binder et al. Mol Ther Methods Clin Dev. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

G.K.B. is an employee of Cabaletta Bio, a member of the board of directors of Instil Bio, and a member of the scientific advisory board of Immatics. C.-C.C. is an employee of Cabaletta Bio.

References

    1. Milone M.C., O'Doherty U. Clinical use of lentiviral vectors. Leukemia. 2018;32:1529–1541. doi: 10.1038/s41375-018-0106-0. - DOI - PMC - PubMed
    1. Jadlowsky J.K., Leskowitz R., McKenna S., Karar J., Ma Y., Dai A., Plesa G., Chen F., Alexander K., Petrella J., et al. Long-term stability of clinical-grade lentiviral vectors for cell therapy. Mol. Ther. Methods Clin. Dev. 2024;32 doi: 10.1016/j.omtm.2024.101186. - DOI - PMC - PubMed
    1. Ganser-Pornillos B.K., Pornillos O. Restriction of HIV-1 and other retroviruses by TRIM5. Nat. Rev. Microbiol. 2019;17:546–556. doi: 10.1038/s41579-019-0225-2. - DOI - PMC - PubMed
    1. Levine B.L., Humeau L.M., Boyer J., MacGregor R.R., Rebello T., Lu X., Binder G.K., Slepushkin V., Lemiale F., Mascola J.R., et al. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Natl. Acad. Sci. USA. 2006;103:17372–17377. doi: 10.1073/pnas.0608138103. - DOI - PMC - PubMed
    1. Marcucci K.T., Jadlowsky J.K., Hwang W.T., Suhoski-Davis M., Gonzalez V.E., Kulikovskaya I., Gupta M., Lacey S.F., Plesa G., Chew A., et al. Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology Patients. Mol. Ther. 2018;26:269–279. doi: 10.1016/j.ymthe.2017.10.012. - DOI - PMC - PubMed

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