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. 2024 Dec;136(23-24):647-650.
doi: 10.1007/s00508-024-02335-3. Epub 2024 Mar 8.

Challenging the common practice of intravenous fluid administration : Viewpoint on the need for an enteral fluid therapy trial in critically ill patients

Nikolaus Keil  1 , Vincent Rathkolb  1 , Maximilian Waller  1 , Simon Krenn  2   3 , Georg Hinterholzer  1 , Wilfred Druml  3 , Michael Hiesmayr  4 , Sabine Schmaldienst  1 , Manfred Hecking  3
Affiliations

Challenging the common practice of intravenous fluid administration : Viewpoint on the need for an enteral fluid therapy trial in critically ill patients

Nikolaus Keil et al. Wien Klin Wochenschr. 2024 Dec.
No abstract available

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Conflict of interest statement

Conflict of interest: N. Keil, V. Rathkolb, M. Waller, S. Krenn, G. Hinterholzer, W. Druml, M. Hiesmayr, S. Schmaldienst and M. Hecking declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Study design. a Eligibility criteria for screening: intubation within 72 h and age over 18 years old. b Exclusion criteria: kidney replacement therapy before intubation, inability to receive enteral nutrition, pregnancy, postoperative patients with consecutive intensive care admission, expected required fluid > 4 ml/kg/h for at least 24 h, evidence of gastrointestinal disease, abdominal surgery in the last 3 months. c Anticipated volume of intravenously applied fluids in the intravenous group: 2211 mL/24 h. d Anticipated volume of intravenously applied fluids in the enteral group: 1613 mL/24 h. Anticipated volume of intravenously applied fluid in the enteral group: 1376 mL/24 h. e Primary objectives: incidence and extent of regurgitation. Secondary objectives: serum sodium levels, serum osmolality, renal function parameters, days on ventilation, and mortality
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References

    1. Frost P. Intravenous fluid therapy in adult inpatients. BMJ (Clinical research ed). 2015;350:g7620. - PubMed
    1. Mayerhöfer T, Shaw AD, Wiedermann CJ, Joannidis M. Fluids in the ICU: which is the right one? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association—European Renal Association. 2023;38(7):1603–12. - PMC - PubMed
    1. Finfer S, Myburgh J, Bellomo R. Intravenous fluid therapy in critically ill adults. Nat Rev Nephrol. 2018;14(9):541–57. - PubMed
    1. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical care medicine. 2021;49(11):e1063–e143. - PubMed
    1. Kuttab HI, Lykins JD, Hughes MD, Wroblewski K, Keast EP, Kukoyi O, et al. Evaluation and Predictors of Fluid Resuscitation in Patients With Severe Sepsis and Septic Shock. Crit Care Med. 2019;47(11):1582–90. - PMC - PubMed

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