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Comment
. 2024 Apr;25(2):105-107.
doi: 10.1038/s41435-024-00266-7. Epub 2024 Mar 8.

Getting under the skin: resident memory CD8+ T cells have a second residence in the draining lymph node

Teresa Neuwirth  1   2 , Azuah L Gonzalez  3 , Emilie Fisher-Gupta  3 , Georg Stary  4   5
Affiliations
Comment

Getting under the skin: resident memory CD8+ T cells have a second residence in the draining lymph node

Teresa Neuwirth et al. Genes Immun. 2024 Apr.

Erratum in

No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. CD8+ T cells seed skin and lymph node TRM after infection via the dermal lymphatic vessels.
After infection with VV, CD8+ T cells in the skin recoginze viral antigens and subsequently seed skin TRM and LN TRM. During the effector phase, lymphatic-dependent egress of LN TRM is essnetial for LN TRM seeding. Moreover, LN TRM has a protective role upon rechallenge. Created with BioRender.
See this image and copyright information in PMC

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References

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