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. 2024 Mar 8;19(1):108.
doi: 10.1186/s13023-024-03096-y.

The impact of osteogenesis imperfecta severity on oral health-related quality of life in Spain: a cross-sectional study

Amira Ahmed Elfituri  1 , Manuel Joaquín De Nova  2 , Mohammadamin Najirad  3
Affiliations

The impact of osteogenesis imperfecta severity on oral health-related quality of life in Spain: a cross-sectional study

Amira Ahmed Elfituri et al. Orphanet J Rare Dis. .

Erratum in

Abstract

Background: Osteogenesis imperfecta (OI) affects dental and craniofacial development; therefore, it can influence oral health-related quality of life (OHRQoL). The objective of this study was to explore the influence of the severity of OI on OHRQoL in adults older than eighteen years residing in Spain.

Method: Adults with OI were recruited from the Spanish Association of Crystal Bone (AHUCE) foundation. OHRQoL was evaluated using the Spanish version of the Oral Health Impact Profile questionnaire (OHIP-14sp), oral hygiene habits, and a dental care survey. Clinical and radiological dental examinations were performed to evaluate the patients' oral conditions.

Results: A total of 65 adults (n = 46 females) aged between nineteen and sixty-two years who were diagnosed with OI and classified as type I, III, and IV (n = 20, 14, and 31, respectively) participated in this research. The total OHIP-14sp scores were significantly greater (worse) for type III (23 [SD = 10]) and type IV (21.4 [SD = 12]) than for type I (13.8 [SD = 6]) (P < 0.05). The negative impact of OHRQoL was due to the association of type III OI with all domains except for the handicap domain, while type IV OI was associated with the physical disability, social disability, and handicap domains (P < 0.05 for all).

Conclusion: The severity of OI negatively impacted OHRQoL in adults. This association was statistically significant.

Keywords: Oral health impact profile; Oral health-related quality of life; Osteogenesis Imperfecta.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
A flow chart illustrating the recruitment process
Fig. 2
Fig. 2
Patients with osteogenesis imperfecta (OI): without dentinogenesis imperfecta (confirmed via periapical radiographs) and with a hypoplastic maxilla that led to anterior and posterior crossbite (type IV) (A); an open bite from the left to right second molar (type III) (B); occlusion only on the right side with a crossbite on the occluding side and poor oral hygiene (type III) (C); OI, dentinogenesis imperfecta and posterior crossbite and tendency to anterior open bite (type IV) (D); normal occlusion with a striking tooth color (type IV) (E); and flaring anteroinferior teeth with marked recission (type IV) (F)
See this image and copyright information in PMC

References

    1. Forlino A, Marini JC. Osteogenesis Imperfecta. Lancet. 2016;387(10028):1657–71. doi: 10.1016/S0140-6736(15)00728-X. - DOI - PMC - PubMed
    1. Marini JC, Forlino A, Bächinger HP, Bishop NJ, Byers PH, Paepe A, Fassier F, Fratzl-Zelman N, Kozloff KM, Krakow D, Montpetit K, Semler O. Osteogenesis imperfecta. Nat Rev Dis Primers. 2017;3:17052. 10.1038/nrdp.2017.52. PMID: 28820180. - PubMed
    1. AHUCE foundation [Internet]. that serves individuals with a clinical and/or molecular diagnosis with OI in Spain. Available in: ¿Qué es la osteogénesis imperfecta?| Fundación AHUCE (fundacionahuce.org).
    1. Forlino A, Cabral WA, Barnes AM, Marini JC. New perspectives on osteogenesis imperfecta. Nat Rev Endocrinol. 2011;7(9):540– 57. 10.1038/nrendo.2011.81. PMID: 21670757; PMCID: PMC3443407. - PMC - PubMed
    1. Van Dijk FS, Pals G, Van Rijn RR, Nikkels PG, Cobben JM. Classification of Osteogenesis Imperfecta revisited. Eur J Med Genet. 2010 Jan-Feb;53(1):1–5. 10.1016/j.ejmg.2009.10.007. Epub 2009 Oct 28. PMID: 19878741. - PubMed