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. 2024 Jan 15;86(3):1329-1334.
doi: 10.1097/MS9.0000000000001731. eCollection 2024 Mar.

Prevalence and clinical characteristics of hyperuricemia among patients with chronic kidney disease under haemodialysis in a tertiary care center: a cross-sectional study

Affiliations

Prevalence and clinical characteristics of hyperuricemia among patients with chronic kidney disease under haemodialysis in a tertiary care center: a cross-sectional study

Ayush Mohan Bhattarai et al. Ann Med Surg (Lond). .

Abstract

Background: Hyperuricemia is common in chronic kidney disease patients. This study aimed to investigate the prevalence and clinical characteristics of hyperuricemia in patients with chronic kidney disease undergoing haemodialysis.

Materials and methods: This cross-sectional study was conducted among 104 patients with chronic kidney disease who visited the haemodialysis unit of a tertiary centre hospital from 11 September 2022, to 11 November 2022. A convenience sampling technique was used. The data were collected using a proforma form, entered into, and analyzed using the Statistical Package for Social Sciences version 21.

Results: The mean age group of the study participants was 54.02 ± 14.03 years, and around two-thirds were male (n=70, 67.3%). Almost half of the participants (50, 48.07%) had hyperuricemia with a mean uric acid level of 6.76 ± 2.62 mg/dl. The majority of the participants had associated hypertension (n=100, 96.2%). More than three-fourths of the respondents (83, 79.8%) had haemoglobin levels below the target range.

Conclusion: Nearly half of the study participants had hyperuricemia.

Keywords: Nepal; chronic renal insufficiency; cross-sectional study; hyperuricemia; renal dialysis.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article

Figures

Figure 1
Figure 1
Distribution pattern of haemoglobin and red blood cell indices. MCHC, mean corpuscular haemoglobin concentration; MCV, mean corpuscular volume.
Figure 2
Figure 2
Distribution pattern of electrolytes.
Figure 3
Figure 3
Serum uric acid profile of the participants. IQR, interquartile range.

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References

    1. KDIGO 2012Clinical practice guideline for the evaluation and management of chronic kidney disease. Off J Int Soc Nephrol, 3x. - PubMed
    1. Chuang SY, Chen JH, Yeh WT, et al. . Hyperuricemia and increased risk of ischemic heart disease in a large Chinese cohort. Int J Cardiol 2012;154:316–321. - PubMed
    1. Ohno I. Relationship between hyperuricemia and chronic kidney disease. Nucleosides Nucleotides Nucleic Acids 2011;30:1039–1044. - PubMed
    1. Barbour SJ, Er L, Djurdjev O, et al. . The prevalence of hematologic and metabolic abnormalities during chronic kidney disease stages in different ethnic groups. Kidney Int 2008;74:108–114. - PubMed
    1. Stack AG, Hanley A, Casserly LF, et al. . Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality. QJM 2013;106:647–658. - PubMed