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. 2024 Feb 19;14(2):308-314.
doi: 10.5498/wjp.v14.i2.308.

Risk factors for cognitive impairment in patients with chronic kidney disease

Xiao-Hui Wang  1 , Yong He  1 , Huan Zhou  1 , Ting Xiao  1 , Ran Du  2 , Xin Zhang  3
Affiliations

Risk factors for cognitive impairment in patients with chronic kidney disease

Xiao-Hui Wang et al. World J Psychiatry. .

Abstract

Background: Chronic kidney disease (CKD) patients have been found to be at risk of concurrent cognitive dysfunction in previous studies, which has now become an important public health issue of widespread concern.

Aim: To investigate the risk factors for concurrent cognitive dysfunction in patients with CKD.

Methods: This is a prospective cohort study conducted among patients with CKD between October 2021 and March 2023. A questionnaire was formulated by literature review and expert consultation and included questions about age, sex, education level, per capita monthly household income, marital status, living condition, payment method, and hypertension.

Results: Logistic regression analysis showed that patients aged 60-79 years [odds ratio (OR) = 1.561, P = 0.015] and ≥ 80 years (OR = 1.760, P = 0.013), participants with middle to high school education (OR = 0.820, P = 0.027), divorced or widowed individuals (OR = 1.37, P = 0.032), self-funded patients (OR = 2.368, P = 0.008), and patients with hypertension (OR = 2.011, P = 0.041) had a higher risk of cognitive impairment. The risk of cognitive impairment was lower for those with a college degree (OR = 0.435, P = 0.034) and married individuals.

Conclusion: The risk factors affecting cognitive dysfunction are age, 60-79 years and ≥ 80 years; education, primary school education or less; marital status, divorced or widowed; payment method, self-funded; hypertension; and CKD.

Keywords: Chronic kidney disease; Cognitive dysfunction; Cognitive impairment.

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Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

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References

    1. Olsen E, van Galen G. Chronic Renal Failure-Causes, Clinical Findings, Treatments and Prognosis. Vet Clin North Am Equine Pract. 2022;38:25–46. - PubMed
    1. Ellis P. An overview of haemodialysis. Br J Nurs. 2023;32:356–360. - PubMed
    1. Zhang W, Li P, Zhou H. Mid-short-term risk factors for chronic renal failure in children with posterior urethral valve. Pediatr Surg Int. 2022;38:1321–1326. - PubMed
    1. Flagg AJ. Chronic Renal Therapy. Nurs Clin North Am. 2018;53:511–519. - PubMed
    1. Kanda H, Hirasaki Y, Iida T, Kanao-Kanda M, Toyama Y, Chiba T, Kunisawa T. Perioperative Management of Patients With End-Stage Renal Disease. J Cardiothorac Vasc Anesth. 2017;31:2251–2267. - PubMed