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Case Reports
. 2024 Jan 23;29(5):102215.
doi: 10.1016/j.jaccas.2023.102215. eCollection 2024 Mar 6.

Persistent Prothrombotic State in a Patient With Alström Syndrome

Nihit Shah  1 , Zeina Abu Orabi  1 , Adrian T Warfield  2   3 , Richard Steeds  1   4 , Peysh A Patel  1   4
Affiliations
Case Reports

Persistent Prothrombotic State in a Patient With Alström Syndrome

Nihit Shah et al. JACC Case Rep. .

Abstract

We present the case of a patient with Alström syndrome who was found to have evidence of a prothrombotic state on autopsy after sudden cardiac death. To the best of our knowledge, this case of persistent prothrombotic milieu is the first described in a patient with Alström syndrome.

Keywords: Alström syndrome; CRTD; LV thrombus; persistent prothrombotic state.

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Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
CMR Images CMR images in short-axis (A) and long-axis (B) views showing extensive patchy late gadolinium enhancement. CMR = cardiac magnetic resonance.
Figure 2
Figure 2
TTE TTE in zoomed apical 4 chamber view revealing presence of apical thrombus. TTE = transthoracic echocardiography.
Figure 3
Figure 3
Post-mortem Examination of the Heart (A) Transverse midseptal slice of the left ventricle showing concentric hypertrophy. (B) Right atrium/ventricle opened along the lateral border, revealing pacing lead ensheathed in thrombus. (C) Transverse slice of left ventricle showing thrombus at apex of left ventricle. (D) Main pulmonary trunk opened anteriorly, showing thrombus occluding the origin of the left pulmonary artery.
See this image and copyright information in PMC

References

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