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Case Reports
. 2024 May 1;49(5):454-456.
doi: 10.1097/RLU.0000000000005137. Epub 2024 Mar 6.

Extravasation After [ 177 Lu]Lu-HA-DOTATATE Therapy

Daphne M V de Vries-Huizing  1 , Zing J Cheung  1 , Jeroen J M A Hendrikx, Maarten L Donswijk  1 , Michelle W J Versleijen  1
Affiliations
Case Reports

Extravasation After [ 177 Lu]Lu-HA-DOTATATE Therapy

Daphne M V de Vries-Huizing et al. Clin Nucl Med. .

Abstract

Extravasation of the radiopharmaceutical during peptide receptor radionuclide therapy infusion is an unwanted infrequently reported event. We present the case of a 74-year old woman with a neuroendocrine tumor who was referred for peptide receptor radionuclide therapy. During intravenous infusion of 7.4 GBq [ 177 Lu]Lu-HA-DOTATATE in the upper right arm, extravasation of the radiopharmaceutical occurred through a displaced intravenous catheter. Planar scintigraphy showed pooling of radioactivity in the right upper arm. After 24 hours, the swelling in the arm was decreased; however, erythema was increased. One week later, symptoms had disappeared, and the patient did not experience any complications during follow-up of 11 months.

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Conflict of interest statement

Conflicts of interest and sources of funding: none declared.

References

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