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Review
. 2024 Mar 1:22:101267.
doi: 10.1016/j.fochx.2024.101267. eCollection 2024 Jun 30.

Flow field-flow fractionation coupled with multidetector: A robust approach for the separation and characterization of resistant starch

Mu Wang  1 , Wenhui Zhang  1 , Liu Yang  1 , Yueqiu Li  1 , Hailiang Zheng  2 , Haiyang Dou  1   3   4
Affiliations
Review

Flow field-flow fractionation coupled with multidetector: A robust approach for the separation and characterization of resistant starch

Mu Wang et al. Food Chem X. .

Abstract

The unique properties of resistant starch (RS) have made it applicable in the formulation of a broad range of functional foods. The physicochemical properties of RS play a crucial role in its applications. Recently, flow field-flow fractionation (FlFFF) has attracted increasing interest in the separation and characterization of different categories of RS. In this review, an overview of the theory behind FlFFF is introduced, and the controllable factors, including FlFFF channel design, sample separation conditions, and the choice of detector, are discussed in detail. Furthermore, the applications of FlFFF for the separation and characterization of RS at both the granule and molecule levels are critically reviewed. The aim of this review is to equip readers with a fundamental understanding of the theoretical principle of FlFFF and to highlight the potential for expanding the application of RS through the valuable insights gained from FlFFF coupled with multidetector analysis.

Keywords: Characterization; Flow field-flow fractionation; Resistant starch.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Classification and application of RS.
Fig. 2
Fig. 2
Schematic diagram of the channel (a and b) and separation process (c) of FlFFF.
Fig. 3
Fig. 3
Main separation modes of FlFFF.
See this image and copyright information in PMC

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