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Review
. 2025 Apr;117(4):233-234.
doi: 10.17235/reed.2024.10334/2024.

Syphilitic proctitis: review of the literature

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Free article
Review

Syphilitic proctitis: review of the literature

Liyuan Lv et al. Rev Esp Enferm Dig. 2025 Apr.
Free article

Abstract

Syphilitic proctitis is a rare sexually transmitted disease caused by spirochete pallidum infecting the rectal mucosa. It usually has no specific clinical manifestations and is easily misdiagnosed with other rectal and anal diseases such as rectal cancer, malignant lymphoma, inflammatory bowel disease, etc.. Therefore, diagnosis of the disease is difficult and treatment options are often unreasonable. A case of syphilitic proctitis in our hospital with "rectal mass" as the main manifestation is reported as follows and relevant literature is reviewed. At the same time, we studied and analyzed the clinical and histological characteristics and differential diagnosis of syphilitic proctitis to further deepen the understanding of this disease.

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