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Review
. 2024 Apr:125:102715.
doi: 10.1016/j.ctrv.2024.102715. Epub 2024 Mar 5.

How to manage waldenström's macroglobulinemia in 2024

Alexander Grunenberg  1 , Christian Buske  2
Affiliations
Review

How to manage waldenström's macroglobulinemia in 2024

Alexander Grunenberg et al. Cancer Treat Rev. 2024 Apr.

Abstract

Clinical management of Waldenström's Macroglobulinemia has seen major progress in the recent years, triggered by our improved understanding of the biology of the disease and the development of new therapies. Based on this there are multiple treatment options available for patients with WM ranging from classical immunochemotherapy to targeted approaches blocking key enzymes involved in lymphoma growth. This review summarizes our current knowledge about diagnostics and treatment of this rare but recurrent lymphoma subtype, which often presents a major clinical challenge in daily clinical life.

Keywords: BTK inhibitors; CXCR4; Immunochemotherapy; MYD88; Waldenström’s Macroglobulinemia.

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Conflict of interest statement

Declaration of competing interest Alexander Grunenberg: none Christian Buske: Honoraria: Roche/Genentech, Janssen, BeiGene, Novartis, Pfizer, AbbVie, Gilead Sciences, Celltrion, MorphoSys, Regeneron, Hexal, Bayer, SOBI Consulting or Advisory Role: Gilead Sciences, Janssen, Roche, Pfizer, BeiGene, Celltrion, AbbVie, Regeneron, MorphoSys, Novartis, Bayer, SOBI Speakers' Bureau: Roche, Janssen, BeiGene, Celltrion, AbbVie, Pfizer, Gilead Sciences, Bayer, Hexal, MorphoSys, Regeneron, Novartis Research Funding: Roche/Genentech, Janssen, Celltrion, MSD, Amgen, Bayer (Inst)

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