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. 2024 May;12(3):801-809.
doi: 10.1007/s43390-024-00828-9. Epub 2024 Mar 12.

Association patterns between lumbar paraspinal muscles and sagittal malalignment in preoperative patients undergoing lumbar three-column osteotomy

Thomas Caffard  1   2 , Samuel J Medina  1 , Artine Arzani  1 , Erika Chiapparelli  1 , Lukas Schönnagel  1   3 , Soji Tani  1   4 , Gaston Camino-Willhuber  1 , Jiaqi Zhu  5 , David Dalton  1 , Timo Zippelius  2 , Andrew A Sama  1 , Frank P Cammisa  1 , Federico P Girardi  1 , Alexander P Hughes  6
Affiliations

Association patterns between lumbar paraspinal muscles and sagittal malalignment in preoperative patients undergoing lumbar three-column osteotomy

Thomas Caffard et al. Spine Deform. 2024 May.

Abstract

Purpose: We aim to investigate the associations between lumbar paraspinal muscles and sagittal malalignment in patients undergoing lumbar three-column osteotomy.

Methods: Patients undergoing three-column osteotomy between 2016 and 2021 with preoperative lumbar magnetic resonance imaging (MRI) and whole spine radiographs in the standing position were included. Muscle measurements were obtained using a validated custom software for segmentation and muscle evaluation to calculate the functional cross-sectional area (fCSA) and percent fat infiltration (FI) of the m. psoas major (PM) as well as the m. erector spinae (ES) and m. multifidus (MM). Spinopelvic measurements included pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), L1-S1 lordosis (LL), T4-12 thoracic kyphosis (TK), spino-sacral angle (SSA), C7-S1 sagittal vertical axis (SVA), T1 pelvic angle (TPA) and PI-LL mismatch (PI - LL). Statistics were performed using multivariable linear regressions adjusted for age, sex, and body mass index (BMI).

Results: A total of 77 patients (n = 40 female, median age 64 years, median BMI 27.9 kg/m2) were analyzed. After adjusting for age, sex and BMI, regression analyses demonstrated that a greater fCSA of the ES was significantly associated with greater SS and SSA. Moreover, our results showed a significant correlation between a greater FI of the ES and a greater kyphosis of TK.

Conclusion: This study included a large patient cohort with sagittal alignment undergoing three-column osteotomy and is the first to demonstrate significant associations between the lumbar paraspinal muscle parameters and global sagittal alignment. Our findings emphasize the importance of the lumbar paraspinal muscles in sagittal malalignment.

Keywords: Fat infiltration; Functional cross-sectional area; Lumbar paraspinal muscles; Lumbar three-column osteotomy; Sacral slope; Spino-sacral angle.

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