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. 2024 Mar;30(3):e14588.
doi: 10.1111/cns.14588.

Long term for patients with futile endovascular reperfusion after stroke

Mengke Zhang  1 , Ruiwen Che  2 , Jiali Xu  3 , Wenting Guo  4 , Xi Chen  1 , Wenbo Zhao  1 , Changhong Ren  5 , Milan Jia  1 , Xunming Ji  5   6
Affiliations

Long term for patients with futile endovascular reperfusion after stroke

Mengke Zhang et al. CNS Neurosci Ther. 2024 Mar.

Abstract

Aims: With the progress of thrombectomy technology, the vascular recanalization rate of patients with stroke has been continuously improved, but the proportion of futile recanalization (FR) is still quite a few. The long-term prognosis and survival of patients with FR and its influencing factors remain unclear.

Methods: Consecutive patients who received endovascular treatment (EVT) for ischemic stroke were enrolled between 2013 and 2021 from a single-center prospectively registry study. We evaluated the long-term outcome of these patients by Kaplan-Meier survival analysis, and the multivariable logistic regression curve was performed to analyze influencing factors.

Results: Among 458 patients with FR, 56.4% of patients survived at 1 year, and 50.4% at 2 years. In the multivariate regression analysis, age, premorbid modified Rankin Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), posterior circulation infarct, general anesthesia, symptomatic intracerebral hemorrhage (sICH), and decompressive craniectomy were found to be related to unfavorable outcomes in long-term. Age, premorbid mRS, NIHSS, general anesthesia, and sICH were predictors of long-term mortality.

Conclusions: Futile recanalization accounts for a large proportion of stroke patients after thrombectomy. This study on the long-term prognosis of such patients is beneficial to the formulation of treatment plans and the prediction of therapeutic effects.

Keywords: endovascular therapy; futile recanalization; long-term outcome; stroke.

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Conflict of interest statement

The authors claim no disclosures in this manuscript.

Figures

FIGURE 1
FIGURE 1
Kaplan–Meier estimate of survival probability in patients with FR.
See this image and copyright information in PMC

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