Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2024 Mar 5:18:555-564.
doi: 10.2147/PPA.S445534. eCollection 2024.

Medication Adherence in Children with Asthma

Affiliations
Review

Medication Adherence in Children with Asthma

Paddy McCrossan et al. Patient Prefer Adherence. .

Abstract

Asthma is the most common chronic disease in childhood. If untreated, asthma can lead to debilitating daily symptoms which affect quality of life, but more importantly can lead to fatal asthma attacks which unfortunately still occur globally. The most effective treatment strategy for controlling asthma is for the patient to follow a personalised asthma action plan (PAAP) which will invariably include regular use of an inhaled corticosteroid. To examine medication adherence in children with asthma, we collated recent evidence from systematic reviews in this area to address the following 5 key questions; What is adherence? Is there evidence that children are not adhering to preventer medication? Why is adherence poor and what are the barriers to adherence? Does good adherence improve outcomes in asthma? And lastly, how can treatment adherence be improved?

Keywords: adherence; asthma; children; inhaled corticosteroid; inhaler.

PubMed Disclaimer

Conflict of interest statement

The Queen’s University Belfast spin-out company Continga® provides vDOT services in the UK (https://www.continga.co.uk/). MS and JMcE are co-founders and directors of Continga®. The authors report no other conflicts of interest in this work.

References

    1. Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380(9859):2163. - PMC - PubMed
    1. Warke TJ, Fitch PS, Brown V, et al. Exhaled nitric oxide correlates with airway eosinophils in childhood asthma. Thorax. 2002;57(5):383–387. doi:10.1136/thorax.57.5.383 - DOI - PMC - PubMed
    1. Reddel HK, Bacharier LB, Bateman ED, et al. Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes. Am J Respir Crit Care Med. 2022;205(1):17–35. doi:10.1164/rccm.202109-2205PP - DOI - PMC - PubMed
    1. Zhang D, Zheng J. The burden of childhood asthma by age group, 1990–2019: a systematic analysis of global burden of disease 2019 data. Front Pediatrics. 2022;10:113. - PMC - PubMed
    1. Society BT. Scottish intercollegiate guidelines network. Br Guideline Management Asthma. 2016;58.