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Case Reports
. 2024 Feb 11;16(2):e54016.
doi: 10.7759/cureus.54016. eCollection 2024 Feb.

Persistent Pulmonary Hypertension of Newborns Secondary to Labile Hypoxemia Associated With Cyanosis: A Case Series

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Case Reports

Persistent Pulmonary Hypertension of Newborns Secondary to Labile Hypoxemia Associated With Cyanosis: A Case Series

Anushka P Bhagwat et al. Cureus. .

Abstract

Persistent pulmonary hypertension of the newborn (PPHN) is a condition that can be fatal, marked by increased pulmonary vascular resistance that causes blood to shunt from the right to the left. Six infants that present with PPHN due to labile hypoxemia and related cyanosis are examined in this case series. Clinical manifestations, such as premature deliveries, maternal problems, and different reactions to early therapies, are revealed by perinatal and postnatal histories. The newborns' respiratory distress prompted the use of oxygen supplementation and continuous positive airway pressure (CPAP), but intubation was required due to continued hypoxemia. The series aims to establish a way for further study in this crucial area while offering insightful contributions to the clinical subtleties of PPHN and illustrating the importance of specific therapeutic approaches.

Keywords: bronchopulmonary dysplasia; chest physiotherapy; high-risk neonates; nrds; pphn.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Vibration for the different lobes
Figure 2
Figure 2. Percussion with percussion cup
Figure 3
Figure 3. Vojta method with percussion

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References

    1. Patient characteristics in persistent pulmonary hypertension of the newborn. Roofthooft MT, Elema A, Bergman KA, Berger RM. Pulm Med. 2011;2011:858154. - PMC - PubMed
    1. Persistent pulmonary hypertension of the newborn in the era before nitric oxide: practice variation and outcomes. Walsh-Sukys MC, Tyson JE, Wright LL, et al. Pediatrics. 2000;105:14–20. - PubMed
    1. Persistent pulmonary hypertension of the newborn with transposition of the great arteries. Roofthooft MT, Bergman KA, Waterbolk TW, Ebels T, Bartelds B, Berger RM. Ann Thorac Surg. 2007;83:1446–1450. - PubMed
    1. Milrinone for persistent pulmonary hypertension of the newborn. Bassler D, Kreutzer K, McNamara P, Kirpalani H. Cochrane Database Syst Rev. 2010;2010:0. - PMC - PubMed
    1. Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. Neonatal Inhaled Nitric Oxide Study Group. N Engl J Med. 1997;336:597–604. - PubMed

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