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Review
. 2024 Mar 8:17:953-963.
doi: 10.2147/JPR.S445171. eCollection 2024.

Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China

Ke Ma #  1 , Zhixiang Cheng #  2 , Hao Jiang #  3 , Zhangya Lin #  4 , Chuansheng Liu #  5 , Xianguo Liu #  6 , Lijuan Lu #  7 , Yan Lu #  8 , Wei Tao #  9 , Suoliang Wang #  10 , Xiaoqiu Yang #  11 , Qishan Yi #  12 , Xiaomei Zhang #  13 , Ying Zhang #  14 , Yanqing Liu #  15
Affiliations
Review

Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China

Ke Ma et al. J Pain Res. .

Abstract

Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. Although ion channel drugs have been proven safe and effective in clinical practice, uncertainty remains regarding its use to treat chronic pain. To standardize the clinical practice of ion channel drug for the treatment of chronic pain, the National Health Commission Capacity Building and Continuing Education Center for Pain Diagnosis and Treatment Special Ability Training Project established an expert group to form an expert consensus on the use of ion channel drugs for the treatment of chronic pain after repeated discussions on existing medical evidence combined with the well clinical experience of experts. The consensus provided information on the mechanism of action of ion channel drugs and their recommendations, caution use, contraindications, and precautions for their use in special populations to support doctors in their clinical decision-making.

Keywords: chronic pain; ion channel drugs; voltage-gated calcium channels; voltage-gated sodium channel.

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Conflict of interest statement

The authors declare that they have no competing interests in this work.

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