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. 2024:2783:35-52.
doi: 10.1007/978-1-0716-3762-3_4.

Soft Tissue Reconstruction

Mario Alessandri-Bonetti  1 , Francesco M Egro  1 , Kacey G Marra  2   3   4
Affiliations

Soft Tissue Reconstruction

Mario Alessandri-Bonetti et al. Methods Mol Biol. 2024.

Abstract

Autologous fat transplantation has revolutionized soft tissue reconstruction, but conventional methods remain unpredictable as graft resorption rates are high due to lack of vascularization. The advent of adipose-derived stem cells (ASCs) has led to improvement of fat grafting outcomes, in part to their ability to undergo facile differentiation into adipose tissue, their angiogenic properties, and their ability to express and secrete multiple growth factors. This chapter discusses the isolation and characterization of human ASCs, its expansion in vitro, and relevant in vivo models for adipose tissue engineering.

Keywords: Adipose tissue; Mesenchymal stem cells; Reconstruction.

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References

    1. Tagliacozzi G (1597) De curtorum chirurgia per insitionem, libri duo. In quibus ea omnia, quae ad hujus chirurgiae, narium scilicet, aurium, ac labiorum per insitionem restaurandorum cum theoricen, tum practicen pertinere videbantur, clarissima methodo cumulatissime declarantur. Additis cutis traducis instrumentorum omnium, atque deligationum iconibus, & tabulis. Venetiis,: Apud Gasparem Bindonum, juniorem. 28 , 94, 95, 47, 32 p
    1. Finch GD, Dawe CJ (2003) Hemiatrophy. J Pediatr Orthop 23(1):99–101 - PubMed - DOI
    1. Baudinne P, Bovy GL, Wasterlain A (1967) Un cas de syndrome de Poland [A case of Poland’s syndrome]. Acta Paediatr Belg 21(5):407–410 - PubMed
    1. Mirzabeigi MN, Wilson AJ, Fischer JP et al (2015) Predicting and managing donor-site wound complications in abdominally based free flap breast reconstruction: improved outcomes with early reoperative closure. Plast Reconstr Surg 135(1):14–23 - PubMed - DOI
    1. Vega S, Smartt JM Jr, Jiang S et al (2008) 500 consecutive patients with free TRAM flap breast reconstruction: a single surgeon’s experience. Plast Reconstr Surg 122(2):329–339 - PubMed - DOI

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