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. 2024 Aug 15;210(4):392-400.
doi: 10.1164/rccm.202401-0048PP.

The Role of Inflammation and Fibrosis in Interstitial Lung Disease Treatment Decisions

Juergen Behr  1 , Margaret L Salisbury  2 , Simon L F Walsh  3 , Anna J Podolanczuk  4 , Lida P Hariri  5   6 , Gary M Hunninghake  7 , Martin Kolb  8 , Christopher J Ryerson  9 , Vincent Cottin  10 , Mary B Beasley  11 , Tamera Corte  12   13 , Allan R Glanville  14 , Ayodeji Adegunsoye  15   16 , Cory Hogaboam  17 , Wim A Wuyts  18 , Imre Noth  19 , Justin M Oldham  20 , Luca Richeldi  21   22 , Ganesh Raghu  23   24 , Athol U Wells  25
Affiliations

The Role of Inflammation and Fibrosis in Interstitial Lung Disease Treatment Decisions

Juergen Behr et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Drivers of first-line treatment decision.
Figure 2.
Figure 2.
(A) Axial HRCT image of the lung bases in a patient with IPF. The high-density regions highlighted by the red arrows have “texture”; that is, there is fine reticulation within, creating a ground glass–like appearance. This represents fine reticulation caused by intralobular septal thickening due to fibrosis. (B) Axial HRCT image just below the level of the carina in a patient with nonspecific interstitial pneumonia. In contrast, amorphous ground-glass opacities are demonstrated (red arrows) without “structure”; that is, the textured appearance seen in A is absent. This ground-glass opacification represents inflammatory infiltrate. HRCT = high-resolution computed tomography.
Figure 3.
Figure 3.
Future matrix for evaluation of treatment decisions in ILD. EB-OCT = endobronchial optical coherence tomography; HRCT = high-resolution computed tomography; ILD = interstitial lung disease.
See this image and copyright information in PMC

References

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MeSH terms