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Review
. 2024 May 2;84(9):1396-1403.
doi: 10.1158/0008-5472.CAN-23-2657.

NCI Cancer Research Data Commons: Cloud-Based Analytic Resources

David Pot #  1 , Zelia Worman #  2 , Alexander Baumann #  3 , Shirish Pathak  4 , Rowan Beck  2 , Erin Beck  5 , Katherine Thayer  3 , Tanja M Davidsen  5 , Erika Kim  5 , Brandi Davis-Dusenbery  2 , John Otridge  4 , Todd Pihl  4 ; CRDC Program; Jill S Barnholtz-Sloan #  5   6 , Anthony R Kerlavage #  5
Affiliations
Review

NCI Cancer Research Data Commons: Cloud-Based Analytic Resources

David Pot et al. Cancer Res. .

Abstract

The NCI's Cloud Resources (CR) are the analytical components of the Cancer Research Data Commons (CRDC) ecosystem. This review describes how the three CRs (Broad Institute FireCloud, Institute for Systems Biology Cancer Gateway in the Cloud, and Seven Bridges Cancer Genomics Cloud) provide access and availability to large, cloud-hosted, multimodal cancer datasets, as well as offer tools and workspaces for performing data analysis where the data resides, without download or storage. In addition, users can upload their own data and tools into their workspaces, allowing researchers to create custom analysis workflows and integrate CRDC-hosted data with their own. See related articles by Brady et al., p. 1384, Wang et al., p. 1388, and Kim et al., p. 1404.

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Figures

Figure 1. The NCI Cloud Resources. Each CR provides unique features to collectively support users across varying levels of technical expertise and access to diverse sets of NCI data. FireCloud and SB-CGC offer extensive repositories of prebuilt tools, tutorials, and workflows in CWL and WDL that provide more assistance to beginners to the cloud, while ISB-CGC is designed for the more advanced user to easily combine new data with tabulated derived data to gain new insights. Users can bring their own data to “Secure Workspaces” and combine it with NCI cloud-hosted “Data” using the analysis “Cloud-Based Tools” readily available at each CR.
Figure 1.
The NCI Cloud Resources. Each CR provides unique features to collectively support users across varying levels of technical expertise and access to diverse sets of NCI data. FireCloud and SB-CGC offer extensive repositories of prebuilt tools, tutorials, and workflows in CWL and WDL that provide more assistance to beginners to the cloud, while ISB-CGC is designed for the more advanced user to easily combine new data with tabulated derived data to gain new insights. Users can bring their own data to “Secure Workspaces” and combine it with NCI cloud-hosted “Data” using the analysis “Cloud-Based Tools” readily available at each CR.
See this image and copyright information in PMC

References

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