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. 2024 Mar 15:10:e52093.
doi: 10.2196/52093.

Using EpiCore to Enable Rapid Verification of Potential Health Threats: Illustrated Use Cases and Summary Statistics

Affiliations

Using EpiCore to Enable Rapid Verification of Potential Health Threats: Illustrated Use Cases and Summary Statistics

Nomita Divi et al. JMIR Public Health Surveill. .

Abstract

Background: The proliferation of digital disease-detection systems has led to an increase in earlier warning signals, which subsequently have resulted in swifter responses to emerging threats. Such highly sensitive systems can also produce weak signals needing additional information for action. The delays in the response to a genuine health threat are often due to the time it takes to verify a health event. It was the delay in outbreak verification that was the main impetus for creating EpiCore.

Objective: This paper describes the potential of crowdsourcing information through EpiCore, a network of voluntary human, animal, and environmental health professionals supporting the verification of early warning signals of potential outbreaks and informing risk assessments by monitoring ongoing threats.

Methods: This paper uses summary statistics to assess whether EpiCore is meeting its goal to accelerate the time to verification of identified potential health events for epidemic and pandemic intelligence purposes from around the world. Data from the EpiCore platform from January 2018 to December 2022 were analyzed to capture request for information response rates and verification rates. Illustrated use cases are provided to describe how EpiCore members provide information to facilitate the verification of early warning signals of potential outbreaks and for the monitoring and risk assessment of ongoing threats through EpiCore and its utilities.

Results: Since its launch in 2016, EpiCore network membership grew to over 3300 individuals during the first 2 years, consisting of professionals in human, animal, and environmental health, spanning 161 countries. The overall EpiCore response rate to requests for information increased by year between 2018 and 2022 from 65.4% to 68.8% with an initial response typically received within 24 hours (in 2022, 94% of responded requests received a first contribution within 24 h). Five illustrated use cases highlight the various uses of EpiCore.

Conclusions: As the global demand for data to facilitate disease prevention and control continues to grow, it will be crucial for traditional and nontraditional methods of disease surveillance to work together to ensure health threats are captured earlier. EpiCore is an innovative approach that can support health authorities in decision-making when used complementarily with official early detection and verification systems. EpiCore can shorten the time to verification by confirming early detection signals, informing risk-assessment activities, and monitoring ongoing events.

Keywords: crises; crisis; crowdsource; crowdsourcing; detect; detection; digital health; disease surveillance; early detection; epidemic intelligence, risk assessment; outbreak; outbreaks; risk; risks; surveillance; threat; threats; verification; warning; warnings.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
Illustration of key steps in the EpiCore verification process. RFI: request for information.
Figure 2
Figure 2
Map of frequency of EpiCore RFIs by location of potential event between 2018 and 2022. RFIs represented in this map are generated by EpiCore requesters for additional input for verification by EpiCore responders. The map is not a representation of all potential health events during the observed period, but is limited to the subset of events identified by the requesters on EpiCore. RFI: request for information.
Figure 3
Figure 3
Timeline of information provided on EpiCore along with other key releases of information from authorities during the early days of the COVID-19 pandemic. Dec: December; HK: Hong Kong; Jan: January; MOH: Ministry of Health; RFI: request for information; WHO: World Health Organization.

References

    1. Defining collaborative surveillance: a core concept for strengthening the global architecture for health emergency preparedness, response, and resilience (HEPR) World Health Organization. 2023. [2024-02-26]. https://www.who.int/publications/i/item/9789240074064 .
    1. Quadripartite one health intelligence scoping study: final report. Food and Agriculture Organization of the United Nations. 2023. [2024-02-26]. https://www.fao.org/documents/card/en/c/cc4480en .
    1. Morgan OW, Abdelmalik P, Perez-Gutierrez E, Fall IS, Kato M, Hamblion E, Matsui T, Nabeth P, Pebody R, Pukkila J, Stephan M, Ihekweazu C. How better pandemic and epidemic intelligence will prepare the world for future threats. Nat Med. 2022;28(8):1526–1528. doi: 10.1038/s41591-022-01900-5. https://europepmc.org/abstract/MED/35764683 10.1038/s41591-022-01900-5 - DOI - PMC - PubMed
    1. Brownstein JS, Rader B, Astley CM, Tian H. Advances in artificial intelligence for infectious-disease surveillance. N Engl J Med. 2023;388(17):1597–1607. doi: 10.1056/NEJMra2119215. https://www.nejm.org/doi/full/10.1056/NEJMra2119215 - DOI - DOI - PubMed
    1. Chan EH, Brewer TF, Madoff LC, Pollack MP, Sonricker AL, Keller M, Freifeld CC, Blench M, Mawudeku A, Brownstein JS. Global capacity for emerging infectious disease detection. Proc Natl Acad Sci U S A. 2010;107(50):21701–21706. doi: 10.1073/pnas.1006219107. https://www.pnas.org/doi/abs/10.1073/pnas.1006219107?url_ver=Z39.88-2003... 1006219107 - DOI - DOI - PMC - PubMed