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. 1979 May;239(1):161-3.

The role of prostaglandins in platelet-vessel wall interaction

R H Bourgain, R Andries, E Finne
  • PMID: 384949

The role of prostaglandins in platelet-vessel wall interaction

R H Bourgain et al. Arch Int Pharmacodyn Ther. 1979 May.

Abstract

Flurbiprofen, a cyclooxygenase inhibitor, and tranylcypromine, a PGI2 synthetase inhibitor, in topical superfusion over an arterial segment respectively decrease and increase ADP-induced local white platelet thrombus formation. Superfusion of the arterial segment with PGI2 demonstrates a dose-response related inhibition of ADP-induced thrombosis.

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