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. 2024 Apr 25;56(4):657-661.
doi: 10.3724/abbs.2024036.

Arsenic trioxide-induced cardiotoxicity: the protective effect of 2-aminoethoxydiphenyl-borate

Jia Feng  1 , Ruimeng Tian  2 , Guilin Lu  2 , Wenjuan Qin  2
Affiliations

Arsenic trioxide-induced cardiotoxicity: the protective effect of 2-aminoethoxydiphenyl-borate

Jia Feng et al. Acta Biochim Biophys Sin (Shanghai). .
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

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Figure 1
Representative images of CD31 immunofluorescence in the myocardium and Tn-T levels of rats in each group (A) Representative images of CD31 immunofluorescence in the myocardium (×200); blue fluorescence indicates the stained nucleus, and green fluorescence indicates CD31. (B) Tn-T levels in the rats in each group. (C) The absorbance values of CD31 in the rats in each group. * P<0.05: overall comparison between groups; aP<0.05: compared with the control group; bP<0.05: compared with the ATO group; cP<0.05: compared with the low-dose 2-APB group. 2-APBL: low-dose 2-APB group, 2-APBH: high-dose 2-APB group.
None
Figure 2
Representative images of the ultrastructure of the myocardium of rats in each group (A) Control group. (B) 2-APB group. (C) ATO group. (D) Low-dose 2-APB group. (E) High-dose 2-APB group. 2-APB L: low-dose 2-APB group, 2-APBH: high-dose 2-APB group. Magnification, ×3000.
None
Figure 3
The levels of enzymes and products related to oxidative stress in each group (A) SOD: superoxide dismutase. (B) GSH-px: glutathione peroxidase. (C) CAT: catalase. (D) GST: glutathione S-transferase. (E) MDA: malondialdehyde ratio. (F) LOOH: lipid hydroperoxide. * P<0.05: overall comparison between groups; aP<0.05: compared with the control group; bP<0.05: compared with the ATO group; cP<0.05: compared with the low-dose 2-APB group. 2-APBL: low-dose 2-APB group, 2-APBH: high-dose 2-APB group.
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