Arriving at SKINTED (Surgery of the Knee, Injury to the Infrapatellar Branch of the Saphenous Nerve, Traumatic Eczematous Dermatitis): A Case Report
- PMID: 38496181
- PMCID: PMC10944648
- DOI: 10.7759/cureus.54307
Arriving at SKINTED (Surgery of the Knee, Injury to the Infrapatellar Branch of the Saphenous Nerve, Traumatic Eczematous Dermatitis): A Case Report
Abstract
Surgery of the knee, injury to the infrapatellar branch of the saphenous nerve, traumatic eczematous dermatitis (SKINTED) is a postsurgical localized dermatitis specifically linked to total knee arthroplasty (TKA). It is due to autonomic denervation following surgically inflicted nerve injury. It develops several months to years following a surgical trauma. It is being referred to by various names in the literature. Locoregional immune dysfunction due to lymphatic injury after surgery is the currently accepted theory. It must be distinguished from atopic dermatitis, allergic contact dermatitis/sensitization induced by topical medications or implanted metal hypersensitivity dermatitis, and post-traumatic eczema/dermatitis. We present a case of an elderly female patient in her 50s with dry eczematous lesions over the lateral aspect of the surgical incision over both knees developed three months following bilateral total knee replacement (TKR) done in view of osteoarthritis. The patient responded well to topical corticosteroid and emollient treatment. We have also reviewed the literature to provide an overview of potential concepts of etiopathogenesis described in the literature and to clear up any ambiguity surrounding various labels given to this entity.
Keywords: autonomic denervation dermatitis; immunocompromised district; saphenous nerve; skinted; tkr.
Copyright © 2024, R M et al.
Conflict of interest statement
The authors have declared that no competing interests exist.
Figures



Similar articles
-
Eczematous Neurodermatitis Following Total Knee Arthroplasty: Expanding Awareness of a Rare and Underdiagnosed Postoperative Dermatologic Complication.Cureus. 2025 Jun 29;17(6):e86989. doi: 10.7759/cureus.86989. eCollection 2025 Jun. Cureus. 2025. PMID: 40734875 Free PMC article.
-
SKINTED: an uncommon cutaneous complication of total knee replacement.Am J Neurodegener Dis. 2023 Feb 25;12(1):16-22. eCollection 2023. Am J Neurodegener Dis. 2023. PMID: 36937110 Free PMC article.
-
Differentiating Autonomic Denervation Dermatitis From Post-traumatic Eczema: A Case Series of Localized Eczematous Eruptions.Cureus. 2025 Jul 29;17(7):e89021. doi: 10.7759/cureus.89021. eCollection 2025 Jul. Cureus. 2025. PMID: 40896034 Free PMC article.
-
Autonomic Denervation Dermatitis: A Relatively Undocumented 'ADD'itional Complication of Total Knee Replacements and Other Surgeries Around the Knee.Indian J Orthop. 2021 Sep 27;55(5):1068-1075. doi: 10.1007/s43465-021-00520-4. eCollection 2021 Oct. Indian J Orthop. 2021. PMID: 34824706 Free PMC article. Review.
-
The surgical anatomy of the infrapatellar branch of the saphenous nerve in relation to incisions for anteromedial knee surgery.J Bone Joint Surg Am. 2013 Dec 4;95(23):2119-25. doi: 10.2106/JBJS.L.01297. J Bone Joint Surg Am. 2013. PMID: 24306699 Review.
Cited by
-
Eczematous Neurodermatitis Following Total Knee Arthroplasty: Expanding Awareness of a Rare and Underdiagnosed Postoperative Dermatologic Complication.Cureus. 2025 Jun 29;17(6):e86989. doi: 10.7759/cureus.86989. eCollection 2025 Jun. Cureus. 2025. PMID: 40734875 Free PMC article.
References
-
- Explaining a hitherto nameless condition: 'SKINTED'. Verma SB, Mody BS. Clin Exp Dermatol. 2009;34:0–6. - PubMed
-
- Post-traumatic eczema. Mathias CG. Dermatol Clin. 1988;6:35–42. - PubMed
-
- The surgical anatomy of the infrapatellar branch of the saphenous nerve in relation to incisions for anteromedial knee surgery. Kerver AL, Leliveld MS, den Hartog D, Verhofstad MH, Kleinrensink GJ. J Bone Joint Surg Am. 2013;95:2119–2125. - PubMed
Publication types
LinkOut - more resources
Full Text Sources