Updated ACVIM consensus statement on equine herpesvirus-1
- PMID: 38497217
- PMCID: PMC11099706
- DOI: 10.1111/jvim.17047
Updated ACVIM consensus statement on equine herpesvirus-1
Abstract
Equine herpesvirus-1 (EHV-1) is a highly prevalent and frequently pathogenic infection of equids. The most serious clinical consequences of infection are abortion and equine herpesvirus myeloencephalopathy (EHM). The previous consensus statement was published in 2009 and considered pathogenesis, strain variation, epidemiology, diagnostic testing, vaccination, outbreak prevention and control, and treatment. A recent survey of American College of Veterinary Internal Medicine large animal diplomates identified the need for a revision to this original consensus statement. This updated consensus statement is underpinned by 4 systematic reviews that addressed key questions concerning vaccination, pharmaceutical treatment, pathogenesis, and diagnostic testing. Evidence for successful vaccination against, or effective treatment of EHV-1 infection was limited, and improvements in experimental design and reporting of results are needed in future studies of this important disease. This consensus statement also updates the topics considered previously in 2009.
Keywords: abortion; diagnosis; equine; equine herpesvirus myeloencephalopathy; herpesvirus‐1; rhinopneumonitis; therapy; vaccination; viremia.
© 2024 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals LLC on behalf of American College of Veterinary Internal Medicine.
Conflict of interest statement
Authors declare no conflict of interest.
References
-
- Foote CE, Love DN, Gilkerson JR, Whalley JM. Detection of EHV‐1 and EHV‐4 DNA in unweaned thoroughbred foals from vaccinated mares on a large stud farm. Equine Vet J. 2004;36:341‐345. - PubMed
-
- Kydd JH, Townsend HG, Hannant D. The equine immune response to equine herpesvirus‐1: the virus and its vaccines. Vet Immunol Immunopathol. 2006;111:15‐30. - PubMed
-
- Slater JD, Lunn DP, Horohov DW, et al. Report of the equine herpesvirus‐1 Havermeyer workshop, San Gimignano, Tuscany, June 2004. Vet Immunol Immunopathol. 2006;111:3‐13. - PubMed
-
- Allen GP, Kydd JH, Slater JD, Smith KC. Equid herpesvirus 1 and equid herpesvirus 4 infections. In: Coetzer JAW, Tustin RC, eds. Infectious Diseases of Livestock. 1st ed. Oxford University Press; 2004:829‐859.
-
- Slater JD. Equine herpesviruses. In: Sellon DC, Long MT, eds. Equine Infectious Diseases. Saunders Elsevier; 2007:134‐152.
