Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Apr-Jun;46(2):e20230120.
doi: 10.1590/2175-8239-JBN-2023-0120en.

Anti-glomerular basement membrane disease in children: can Sars-Cov-2 be a trigger?

[Article in English, Portuguese]
Affiliations
Case Reports

Anti-glomerular basement membrane disease in children: can Sars-Cov-2 be a trigger?

[Article in English, Portuguese]
André Costa Azevedo et al. J Bras Nefrol. 2024 Apr-Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1. Angio-CT scan showing consolidation with atelectasis centered in the apical segments of the lungs.
Figure 2
Figure 2. Large cellular crescents occupy all glomeruli in this biopsy. Focal fibrinoid necrosis (■) and disruption of Bowman capsule (▲) are associated with interstitial inflammation (2A, HE, 200x). The glomerular basement membrane is commonly fragmented in glomeruli with crescents. This can be seen in the silver-stained section (2B, silver-stain, 200x).
Figure 3
Figure 3. Immunofluorescence showing IgG (A), IgM (B), and C3 (C) deposition over the glomerular basement membrane.

References

    1. Dowsett T, Oni L. Anti-glomerular basement membrane disease in children: a brief overview. Pediatr Nephrol. 2022;37(8):1713–9. doi: 10.1007/s00467-021-05333-z. - DOI - PMC - PubMed
    1. McAdoo SP, Pusey CD. Anti-glomerular basement membrane disease. Clin J Am Soc Nephrol. 2017;12(7):1162–72. doi: 10.2215/CJN.01380217. - DOI - PMC - PubMed
    1. Bayat A, Kamperis K, Herlin T. Characteristics and outcome of Goodpasture’s disease in children. Clin Rheumatol. 2012;31(12):1745–51. doi: 10.1007/s10067-012-2062-9. - DOI - PubMed
    1. Menzi CP, Bucher BS, Bianchetti MG, Ardissino G, Simonetti GD. Management and outcomes of childhood Goodpasture’s disease. Pediatr Res. 2018;83(4):813–7. doi: 10.1038/pr.2017.315. - DOI - PubMed
    1. Master Sankar Raj V, Warnecke D, Roberts J, Elhadi S. Antiglomerular basement membrane disease in a pediatric patient: a case report and review of the literature. Case Rep Nephrol. 2017;2017:1256142. doi: 10.1155/2017/1256142. - DOI - PMC - PubMed

Publication types