Declaration of Competing Interest The authors have received support from the following for the production of this manuscript: All support for the present manuscript (eg, funding, provision of study materials, medical writing, article processing charges, etc.) National Institute of General Medical Sciences. Madeleine Kline was supported by award number T32GM144273 from the National Institute of General Medical Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of General Medical Sciences or the National Institutes of Health.