Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;18(4):399-413.
doi: 10.1016/j.jsmc.2023.06.003. Epub 2023 Jul 16.

The Menstrual Cycle and Sleep

Affiliations
Review

The Menstrual Cycle and Sleep

Elisabet Alzueta et al. Sleep Med Clin. 2023 Dec.

Abstract

Aspects of sleep change across the menstrual cycle in some women. Poorer sleep quality in the premenstrual phase and menstruation is common in women with premenstrual symptoms or painful menstrual cramps. Although objective sleep continuity remains unchanged across the regular, asymptomatic menstrual cycle, activity in the sleep electroencephalogram varies, with a prominent increase in sleep spindle activity in the postovulatory luteal phase, when progesterone is present, relative to the follicular phase. Menstrual cycle phase, reproductive stage, and menstrual-related disorders should be considered when assessing women's sleep complaints.

Keywords: Follicular; Luteal; Menstrual cycle; Reproduction; Sleep.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
Schematic representation of changes in hormones and termperature across a typical 28-day ovulatory menstrual cycle, where 1 represent the first day of bleeding and 14 the day of ovulation.

References

    1. Baker FC, Lee KA. Menstrual Cycle Effects on Sleep. Sleep Med Clin. 2018;13(3):283–294. - PubMed
    1. Wood C, Larsen L, Williams R. Menstrual characteristics of 2,343 women attending the Shepherd Foundation. Aust N Z J Obstet Gynaecol. 1979;19(2):107–110. - PubMed
    1. Shughrue PJ, Lane MV, Merchenthaler I. Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system. The Journal of comparative neurology. 1997;388(4):507–525. - PubMed
    1. Curran-Rauhut MA, Petersen SL. The distribution of progestin receptor mRNA in rat brainstem. Brain research Gene expression patterns. 2002;1(3-4):151–157. - PubMed
    1. Mong JA, Baker FC, Mahoney MM, et al. Sleep, rhythms, and the endocrine brain: influence of sex and gonadal hormones. J Neurosci. 2011;31(45):16107–16116. - PMC - PubMed