Making genome editing a success story in Africa

Hussein M Abkallo¹, Patrick Arbuthnot², Thomas O Auer^{3

4}, Dave K Berger⁵, Johan Burger⁶, Ereck Chakauya^{7

8}, Jean-Paul Concordet⁹, Abdoulaye Diabate¹⁰, Vincenzo Di Donato^{11

12}, Jan-Hendrik Groenewald¹³, Amadou Guindo¹⁴, Lizette L Koekemoer¹⁵, Florence Nazare¹⁶, Tony Nolan¹⁷, Fredros Okumu^{18

19}, Emma Orefuwa²⁰, Lily Paemka²¹, Lucia Prieto-Godino^{22

23}, Steven Runo²⁴, Marie Sadler²⁵, Kassahun Tesfaye^{26

27}, Leena Tripathi²⁸, Charles Wondji^{17

29}

Affiliations

¹ International Livestock Research Institute (ILRI), Nairobi, Kenya.
² Wits/SAMRC Antiviral Gene Therapy Research Unit, Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
³ Department of Biology, Faculty of Science and Medicine, University Fribourg, Fribourg, Switzerland. thomas.auer@unifr.ch.
⁴ TReND in Africa, Brighton, UK. thomas.auer@unifr.ch.
⁵ Department of Plant and Soil Sciences, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, South Africa.
⁶ Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.
⁷ Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, South Africa. echakauya@csir.co.za.
⁸ AUDA NEPAD Southern Africa Network for Biosciences (SANBio), Council for Scientific and Industrial Research, Advanced Agriculture and Food Cluster (AAF), Pretoria, South Africa. echakauya@csir.co.za.
⁹ U1154 INSERM, Muséum National d'Histoire Naturelle, Paris, France.
¹⁰ Institut de recherche en sciences de la santé (IRSS), Bobo Dioulasso, Burkina Faso.
¹¹ TReND in Africa, Brighton, UK. vincenzo.didonato@zeclinics.com.
¹² ZeClinics SL. Sant Feliu de Llobregat, Barcelona, Spain. vincenzo.didonato@zeclinics.com.
¹³ Biosafety South Africa, Somerset West, South Africa.
¹⁴ African Center for Excellence in Molecular Engineering, Bamako, Mali.
¹⁵ Wits Research Institute for Malaria, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
¹⁶ African Union Development Agency - NEPAD, Midrand, South Africa.
¹⁷ Liverpool School of Tropical Medicine, Liverpool, UK.
¹⁸ Ifakara Health Institute, Ifakara, Tanzania.
¹⁹ School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.
²⁰ Pan-African Mosquito Association, (PAMCA), KEMRI Headquarters, Nairobi, Kenya.
²¹ University of Ghana, Biochemistry, Cell and Molecular Biology Department, Accra, Ghana.
²² TReND in Africa, Brighton, UK.
²³ The Francis Crick Institute, London, UK.
²⁴ Department of Biochemistry, Microbiology and Biotechnology Kenyatta University, Nairobi, Kenya.
²⁵ Swiss Institute of Bioinformatics, Lausanne, Switzerland.
²⁶ Bio and Emerging Technology Institute, Addis Ababa, Ethiopia.
²⁷ Department of Microbial, Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia.
²⁸ International Institute of Tropical Agriculture (IITA), Nairobi, Kenya.
²⁹ Centre for Research in Infectious Diseases, CRID, Yaoundé, Cameroon.

PMID: 38504013
DOI: 10.1038/s41587-024-02187-2

Making genome editing a success story in Africa

Hussein M Abkallo et al. Nat Biotechnol. 2024 Apr.

. 2024 Apr;42(4):551-554.

doi: 10.1038/s41587-024-02187-2.

Authors

Affiliations

¹ International Livestock Research Institute (ILRI), Nairobi, Kenya.
² Wits/SAMRC Antiviral Gene Therapy Research Unit, Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
³ Department of Biology, Faculty of Science and Medicine, University Fribourg, Fribourg, Switzerland. thomas.auer@unifr.ch.
⁴ TReND in Africa, Brighton, UK. thomas.auer@unifr.ch.
⁵ Department of Plant and Soil Sciences, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, South Africa.
⁶ Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.
⁷ Food Security and Safety Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mmabatho, South Africa. echakauya@csir.co.za.
⁸ AUDA NEPAD Southern Africa Network for Biosciences (SANBio), Council for Scientific and Industrial Research, Advanced Agriculture and Food Cluster (AAF), Pretoria, South Africa. echakauya@csir.co.za.
⁹ U1154 INSERM, Muséum National d'Histoire Naturelle, Paris, France.
¹⁰ Institut de recherche en sciences de la santé (IRSS), Bobo Dioulasso, Burkina Faso.
¹¹ TReND in Africa, Brighton, UK. vincenzo.didonato@zeclinics.com.
¹² ZeClinics SL. Sant Feliu de Llobregat, Barcelona, Spain. vincenzo.didonato@zeclinics.com.
¹³ Biosafety South Africa, Somerset West, South Africa.
¹⁴ African Center for Excellence in Molecular Engineering, Bamako, Mali.
¹⁵ Wits Research Institute for Malaria, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
¹⁶ African Union Development Agency - NEPAD, Midrand, South Africa.
¹⁷ Liverpool School of Tropical Medicine, Liverpool, UK.
¹⁸ Ifakara Health Institute, Ifakara, Tanzania.
¹⁹ School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.
²⁰ Pan-African Mosquito Association, (PAMCA), KEMRI Headquarters, Nairobi, Kenya.
²¹ University of Ghana, Biochemistry, Cell and Molecular Biology Department, Accra, Ghana.
²² TReND in Africa, Brighton, UK.
²³ The Francis Crick Institute, London, UK.
²⁴ Department of Biochemistry, Microbiology and Biotechnology Kenyatta University, Nairobi, Kenya.
²⁵ Swiss Institute of Bioinformatics, Lausanne, Switzerland.
²⁶ Bio and Emerging Technology Institute, Addis Ababa, Ethiopia.
²⁷ Department of Microbial, Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia.
²⁸ International Institute of Tropical Agriculture (IITA), Nairobi, Kenya.
²⁹ Centre for Research in Infectious Diseases, CRID, Yaoundé, Cameroon.

PMID: 38504013
DOI: 10.1038/s41587-024-02187-2

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References

1. van der Oost, J. & Patinios, C. Trends Biotechnol. 41, 396–409 (2023). - DOI - PubMed
1. Martin-Laffon, J., Kuntz, M. & Ricroch, A. E. Nat. Biotechnol. 37, 613–620 (2019). - DOI - PubMed
1. Jhu, M.-Y., Ellison, E. E. & Sinha, N. R. Front. Genome Ed. 5, 1289416 (2023). - DOI - PubMed - PMC
1. Tripathi, J. N., Ntui, V. O. & Tripathi, L. Plant Genome https://doi.org/10.1002/tpg2.20416 (2023). - DOI - PubMed
1. Vernet, A. et al. Nat. Commun. 13, 7963 (2022). - DOI - PubMed - PMC

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Making genome editing a success story in Africa

Affiliations

Making genome editing a success story in Africa

Authors

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References

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LinkOut - more resources

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