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. 2024 Mar 18;12(3):E435-E439.
doi: 10.1055/a-2271-2411. eCollection 2024 Mar.

Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study

Hidenori Kimura  1 , Yoichi Yamamoto  2 , Yohei Yabuuchi  3 , Kohei Shigeta  2 , Masao Yoshida  2 , Soichiro Nagao  3 , Akito Noguchi  4 , Yukihiro Morita  4 , Shuhei Shintani  4 , Osamu Inatomi  4 , Hiroyuki Ono  2 , Akira Andoh  4
Affiliations

Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study

Hidenori Kimura et al. Endosc Int Open. .

Abstract

Several cases have been reported that suggest the efficacy of gel immersion endoscopic mucosal resection (GI-EMR) for gastric neoplasms. However, no study has evaluated treatment outcomes of GI-EMR for gastric neoplasms. This study aimed to investigate the efficacy and safety of GI-EMR for early gastric neoplasms. Nine patients (17 lesions) undergoing gastric GI-EMR were included, with a median lesion size of 10 mm (interquartile range [IQR] 5-13 mm). All lesions were protruding or flat elevated. The median procedure time was 3 minutes (IQR 2-5) and en bloc resection was achieved in all cases. Among 15 neoplastic lesions, the R0 resection rate was 86.7% (13/15 lesions). Adverse events included immediate bleeding requiring hemostasis in two cases, which was controlled endoscopically. No delayed bleeding or perforation occurred. In conclusion, GI-EMR may be a safe and effective treatment for early, small gastric neoplasms. However, due to the small sample in the present study, further investigation is required regarding the indication for this technique.

Keywords: Endoscopic resection (ESD, EMRc, ...); Endoscopy Upper GI Tract; Precancerous conditions & cancerous lesions (displasia and cancer) stomach.

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Conflict of interest statement

Conflict of Interest The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
GI-EMR procedure. a A whitish flat elevated lesion at the greater curvature of the upper gastric body with fundic gland polyposis in a FAP patient. b NBI view. c Marking was performed. d Snaring under gel immersion (the lesion was yellow arrowhead). e Mucosal defect without perforation. GI-EMR, gel immersion endoscopic mucosal resection; FAP, familial adenomatous polyposis; NBI, narrowband imaging
See this image and copyright information in PMC

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