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Case Reports
. 2024 Feb 17;16(2):e54374.
doi: 10.7759/cureus.54374. eCollection 2024 Feb.

An Unusual Presentation of Villoglandular Papillary Adenocarcinoma in a Perimenopausal Woman

Priya R Nair  1 , Saunitra A Inamdar  1 , Minal A Kalambe  1 , Aakanksha Dewangan  1
Affiliations
Case Reports

An Unusual Presentation of Villoglandular Papillary Adenocarcinoma in a Perimenopausal Woman

Priya R Nair et al. Cureus. .

Abstract

Villoglandular papillary adenocarcinoma (VPA) or villoglandular adenocarcinoma (VGA) is a rare but well-recognized subtype of cervical carcinoma. It exhibits a favorable prognosis, particularly within the childbearing age group, and is considered a rare manifestation of mucinous adenocarcinoma typically observed in individuals of reproductive age. In comparison to other adenocarcinomas, VPA generally demonstrates a more optimistic prognosis. This report details the case of a 46-year-old perimenopausal woman who presented with complaints of irregular menses and a protruding mass from the vagina. Upon examination, an exophytic growth was identified, replacing the cervix. A biopsy confirmed the diagnosis of VPA. Subsequently, the patient underwent a radical hysterectomy, followed by post-operative radiation therapy.

Keywords: cervical cancer; endocervicitis; malignancy; perimenopausal woman; radical hysterectomy; villoglandular papillary adenocarcinoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Ultrasonography showing bulky uterus with thickened lower uterine segment and cervix
The arrows show a thickened lower segment of the uterus, and the asterisk shows a thickened cervix.
Figure 2
Figure 2. Axial CT of the patient
The arrow shows the bulky uterus with no parametrial invasion. CT: Computerized tomography
Figure 3
Figure 3. Sagittal view of carcinoma cervix showing bulky uterus with mass in cervix
The top arrow shows the involvement of the lower uterine segment and the bottom arrow shows the cervix.
See this image and copyright information in PMC

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